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Hematopoietic Cell Transplantation for Immune Tolerance in Kidney Transplant Recipients
Study Summary
This trial will test if patients with a functioning kidney transplant and a matching donor can discontinue immunosuppressive drugs while maintaining normal renal function.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have had cancer before, but not skin cancer.I agree to use birth control for 18 months after my transplant.I am over 18, had a kidney transplant from a sibling, and my donor is still available. I've had no rejection.I am not allergic or sensitive to rabbit ATG or radiation treatments.I have had a kidney transplant rejected or my original kidney disease came back.My donor and I are a complete HLA match according to Stanford's lab.My kidney biopsy shows rejection, disease recurrence, or significant scarring.I am over 18, had a kidney transplant from a sibling, and my donor is still available without any history of rejection.I agree to use birth control for 18 months after my transplant.
- Group 1: Immune tolerance, Kidney transplantation
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What health risks have been identified with Total Lymphoid irradiation?
"Due to the limited data on safety and efficacy, our experts at Power rated Total Lymphoid Irradiation a 1 out of 3."
How many participants are currently enrolled in this research endeavor?
"Affirmative. According to clinicaltrials.gov, this research project is searching for 25 participants across a single location and was recently updated on May 6th 2022 since its initial post date of September 13th 2018."
Are there still openings available for prospective participants in this experiment?
"According to the data hosted on clinicaltrials.gov, this medical study is actively recruiting participants. It was first posted in September 2018 and its latest amendment occurred in May 2022."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
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