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Spatial Localization and Mapping (SLAM) and object recognition technology

Navigation System for Vision Impairment (SLAM Trial)

N/A
Recruiting
Led By Seth Billings, Ph.D.
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Subject has the cognitive and communication ability to participate in the study (i.e., follow spoken directions, perform tests, and give feedback)
Subject is willing to conduct psychophysics testing up to 4-6 hours per day of testing on 3-5 consecutive days
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 minutes
Awards & highlights

SLAM Trial Summary

This trial will test a new way to help people with retinal prosthetics better navigate their environment.

Who is the study for?
This trial is for adults with vision impairments or specific conditions like Retinitis Pigmentosa who can follow instructions, give feedback, and speak English. They should be able to participate in testing for up to 6 hours a day over several days, walk unassisted, have good cognitive abilities, and visual acuity of at least 20/40 when corrected.Check my eligibility
What is being tested?
The study tests a navigation system that uses Spatial Localization and Mapping (SLAM) technology along with object recognition to help users of visual prostheses navigate their environment. It will involve both sighted individuals using VR headsets and actual prosthesis users.See study design
What are the potential side effects?
Since this trial involves non-invasive technology rather than medication or surgery, traditional side effects are not expected. Participants may experience discomfort from prolonged use of VR headsets or fatigue from extensive testing sessions.

SLAM Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can follow instructions and communicate my thoughts clearly.
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I am willing to undergo testing for 4-6 hours a day over 3-5 days.
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I am at least 18 years old.
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I can walk by myself without help.
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I understand the study information and can give my consent in writing.
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I am at least 18 years old.

SLAM Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~trial duration: estimated at up to one minute.
This trial's timeline: 3 weeks for screening, Varies for treatment, and trial duration: estimated at up to one minute. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Accuracy as assessed as ratio of target identification success to total trials
Success in psychophysical judgments
Trial Time as assessed by mean time duration to identify target

SLAM Trial Design

1Treatment groups
Experimental Treatment
Group I: Navigation system for users of a visual prosthesisExperimental Treatment1 Intervention
This intervention will assess the feasibility of using a navigation system to aid blind users of a visual prosthesis with navigation tasks, by using the navigation system to provide navigational cues through multiple sensory modalities including vision and audition. The navigation system will be designed and developed as part of the proposed research and will interface with the Argus II retinal prosthesis system, which is an FDA approved visual prosthesis. Existing blind users of the Argus II device will be recruited for this study, and the navigation system will interface with these subjects' existing Argus II systems. Sighted subjects will also be recruited for this study, in which case the navigation system will interface with a head-mounted display (such as the Oculus Rift) worn by the sighted subjects that simulates the visual sensory information experienced by blind users of the Argus II retinal implant.

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Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,245 Previous Clinical Trials
14,816,471 Total Patients Enrolled
3 Trials studying Visual Impairment
434 Patients Enrolled for Visual Impairment
Carnegie Mellon UniversityOTHER
76 Previous Clinical Trials
539,895 Total Patients Enrolled
National Eye Institute (NEI)NIH
546 Previous Clinical Trials
1,401,959 Total Patients Enrolled
2 Trials studying Visual Impairment
670 Patients Enrolled for Visual Impairment

Media Library

Environmental Localization Mapping and Guidance (Spatial Localization and Mapping (SLAM) and object recognition technology) Clinical Trial Eligibility Overview. Trial Name: NCT04359108 — N/A
Visual Impairment Research Study Groups: Navigation system for users of a visual prosthesis
Visual Impairment Clinical Trial 2023: Environmental Localization Mapping and Guidance Highlights & Side Effects. Trial Name: NCT04359108 — N/A
Environmental Localization Mapping and Guidance (Spatial Localization and Mapping (SLAM) and object recognition technology) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04359108 — N/A
Visual Impairment Patient Testimony for trial: Trial Name: NCT04359108 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any open enrollment opportunities for this medical trial?

"Indeed, the information on clinicaltrials.gov indicates that this trial is actively enrolling volunteers. The study was initially posted in March 2021 and has been updated as recently as June 2022. Currently, 35 participants need to be signed up from 2 different medical centers."

Answered by AI

How many participants have been incorporated into this research project?

"Affirmative. Clinicaltrials.gov records that this medical trial, which launched on March 16th 2021, is currently enrolling patients. There are a total of 35 individuals required from 2 distinct clinical sites."

Answered by AI

May I be included in this trial based on my qualifications?

"This clinical trial seeks 35 individuals, aged 18 and 100, with a visually prosthetic implant. Necessary criteria include the ability to converse in English; being an adult of 25 years or older; having adequate cognitive capability to comprehend study information and provide written consent; possessing visual acuity at least 20/40 (after correction); enduring up to 6 hours per day of psychophysics testing across 3-5 consecutive days; mobility without aid; as well as Argus II surgeon clearance for programming post eye surgery healing."

Answered by AI

Does this trial allow for geriatric patients to participate?

"This medical study is looking for individuals between 18 and 100 years old. There are 30 trials that cater to the younger demographic, while 78 studies focus on patients past their senior years."

Answered by AI

Who else is applying?

What state do they live in?
Washington
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

Looking for opportunities to cure retinitis pigmantosa.
PatientReceived 2+ prior treatments
~3 spots leftby Jul 2024