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Behavioral Intervention

Tough Talks COVID for Increasing COVID-19 Vaccine Uptake among African American Young Adults in the South

Waitlist Available
Led By Lisa Hightow-Weidman, MD, MPH
Research Sponsored by Florida State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Identify as African American/Black
Be between 18 and 65 years old
Must not have
Be younger than 18 years old
Be older than 65 years old
Screening 3 weeks
Treatment Varies
Follow Upmonth 3
Awards & highlights
No Placebo-Only Group

Study Summary

This trial will test a new intervention to increase vaccine uptake among 360 Black young adults from Alabama, Georgia, and North Carolina. The intervention will be compared to the standard of care, and the primary outcome will be vaccine uptake.

Eligible Conditions
  • COVID-19
  • Coronavirus
  • Vaccine Uptake

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You self-identify as an African American/Black person.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~month 3
This trial's timeline: 3 weeks for screening, Varies for treatment, and month 3 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
COVID Vaccine Uptake at Month 1
COVID Vaccine Uptake at Month 3
Secondary outcome measures
COVID Vaccine Confidence
COVID Vaccine Hesitancy

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: TT-C InterventionExperimental Treatment1 Intervention
Research staff will provide access to the TT-COVID app for one-month, which will provide knowledge about the COVID-19 vaccine, address mis-information, and include multi-media digital stories from study participant's peers.
Group II: Standard of Care (Control)Active Control1 Intervention
Research staff will provide COVID vaccine materials from the Centers for Disease Control (CDC) to those participants in the Standard of Care (SOC) arm.

Find a Location

Who is running the clinical trial?

Florida State UniversityLead Sponsor
192 Previous Clinical Trials
29,830 Total Patients Enrolled
National Institute on Minority Health and Health Disparities (NIMHD)NIH
351 Previous Clinical Trials
1,209,378 Total Patients Enrolled
15 Trials studying COVID-19
155,324 Patients Enrolled for COVID-19
University of North Carolina, Chapel HillLead Sponsor
1,461 Previous Clinical Trials
4,128,770 Total Patients Enrolled
8 Trials studying COVID-19
2,972 Patients Enrolled for COVID-19

Media Library

Tough Talks COVID (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05490329 — N/A
COVID-19 Research Study Groups: Standard of Care (Control), TT-C Intervention
COVID-19 Clinical Trial 2023: Tough Talks COVID Highlights & Side Effects. Trial Name: NCT05490329 — N/A
Tough Talks COVID (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05490329 — N/A
COVID-19 Patient Testimony for trial: Trial Name: NCT05490329 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the criteria for joining this clinical research endeavor?

"Patients between 18 and 29 years old, with a confirmed Covid 19 diagnosis, can apply to this clinical trial. Currently, up to 360 individuals are being accepted into the study's cohort."

Answered by AI

Are there any existing opportunities for individuals to join this clinical experiment?

"Unfortunately, the clinicaltrials.gov registry shows that this specific trial is not currently enlisting patients after its most recent update on November 4th 2022. However, there are 1038 other medical studies actively recruiting participants at present."

Answered by AI

Is it feasible for seniors to partake in this medical trial?

"Eligible participants for this study consist of those over 18 years old and under 29."

Answered by AI

Who else is applying?

What state do they live in?
North Carolina
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?

Why did patients apply to this trial?

I wanted to see if there was anything else out there that can help me.
PatientReceived 2+ prior treatments

What questions have other patients asked about this trial?

How long is the trail?
PatientReceived 2+ prior treatments
~40 spots leftby Jan 2024