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Antibiotics for Fetal Hydronephrosis (ALPHA Trial)
ALPHA Trial Summary
This trial looks at whether giving antibiotics to pregnant women who have a fetus with hydronephrosis can help prevent urinary tract infections in the child.
ALPHA Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowALPHA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.ALPHA Trial Design
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Who is running the clinical trial?
Media Library
- I have had kidney failure in the past.I need to use antibiotics regularly for another health condition.My infant has a confirmed kidney issue with a dilated ureter.You are allergic to trimethoprim.My bladder and kidneys do not have severe reflux.My kidney swelling is severe.My infant has posterior urethral valves or Prune-Belly syndrome.I have a duplicated urinary system condition.My child has a moderate to severe urinary reflux.
- Group 1: Trimethoprim
- Group 2: Simple syrup
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many people are participating in this research endeavor?
"At present, this trial is not accepting new candidates. The study was posted on July 1st of 2010 and last updated on April 4th 2022. However, if you are interested in other trials, there are 92 that involve hydronephrosis and 16 studies focusing upon Trimethoprim presently enrolling patients."
Is my profile suited to participate in this clinical experiment?
"This clinical trial welcomes 160 participants who have hydronephrosis and are between 1 month to 7 months of age."
To what ailments is Trimethoprim commonly prescribed?
"Trimethoprim is traditionally used to combat shigella-induced enteritis, however it has been successfully employed in the treatment of otitis media, cholera, and other forms of shigellosis."
Is there space for additional participants in this trial?
"Recruiting for this trial has ceased; it was initially posted on July 1st 2010 and most recently amended April 4th 2022. If you are searching for other trials, there currently exist 92 studies with hydronephrosis accepting patients, as well as 16 studies utilizing Trimethoprim in their research actively admitting individuals."
What precedent has been established regarding Trimethoprim through medical experimentation?
"At the moment, a total of 16 Trimethoprim trials are currently ongoing with 3 in their final stage. Participants can be found at 39 distinct sites with Montreal, Quebec being the primary area for these clinical experiments."
Is this trial open to individuals aged twenty-five and over?
"This trial is recruiting infants that are between 1 and 7 months of age."
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