SPY fluorescent angiography for Constriction, Pathologic

University of Virginia, Charlottesville, VA
Constriction, Pathologic+2 More
SPY fluorescent angiography - Device
All Sexes
Eligible conditions
Constriction, Pathologic

Study Summary

This study is evaluating whether intraoperative use of SPY fluorescent angiography during urinary diversion reduces rate of ureteroenteric stricture.

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Eligible Conditions

  • Constriction, Pathologic
  • Ureteral Obstruction
  • Ureter Stricture

Treatment Effectiveness

Study Objectives

This trial is evaluating whether SPY fluorescent angiography will improve 1 primary outcome and 2 secondary outcomes in patients with Constriction, Pathologic. Measurement will happen over the course of 90 days.

1.5 years
Incidence of Ureteroenteric Stricture
90 days
90 day postoperative readmission
Rate of hydronephrosis, pyelonephritis, or renal impairment

Trial Safety

Trial Design

2 Treatment Groups

Study Arm: SPY fluorescent angiography

This trial requires 50 total participants across 2 different treatment groups

This trial involves 2 different treatments. SPY Fluorescent Angiography is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Study Arm: SPY fluorescent angiography
ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1.5 years
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 1.5 years for reporting.

Who is running the study

Principal Investigator
T. K.
Prof. Tracey Krupski, MD
University of Virginia

Closest Location

University of Virginia - Charlottesville, VA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Undergoing open urinary diversion

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people get constriction, pathologic a year in the United States?

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Results from a recent clinical trial of the present study demonstrate the need to evaluate both incidence and prevalence of Constriction, Pathologic among patients presenting to primary care physicians and Urologists, as well as to examine and characterize factors leading to referral for surgical treatment.

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What causes constriction, pathologic?

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Myocardial constriction following a cardiac myocardial infarction is not common, but in some cases there is evidence that it is responsible for the heart failure in those patients later diagnosed with Brugada syndrome; however, in Brugada ECG no cardiac myo-larike is present.

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Can constriction, pathologic be cured?

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In the event of constrictive pericarditis, the constrictive pattern can be resolved from the cardiomyocyte to a normal pattern over a couple of years, which is in contrast to re-constrictive pericardial disease, which is most likely to resolve over the medium to long term.

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What are the signs of constriction, pathologic?

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This article discusses the signs of constriction, pathologic, and the signs of constriction, pathologic, which may be found when looking at patients undergoing the diagnostic work down.

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What is constriction, pathologic?

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The constriction and a constrictive remodeling are not the same pathological event. Results from a recent clinical trial suggest that in a process of constriction, cells have the option to change phenotype toward a more motile growth. If it is not a reversible process, this new phenotype may change the final morphology of the constrictive remodeling.

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What are common treatments for constriction, pathologic?

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Treatment of constrictive stridor is dependent on the cause of the stricture. Treatment for this condition in a pediatric setting includes correction of the airway or stent placement.

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What does spy fluorescent angiography usually treat?

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In the present study, the spy angiography study helped us to obtain important information for surgical risk reduction: age, obesity, and type of the surgical procedure performed. We would like to emphasize that espionage angiography is a safe method to assess surgical risk in patients undergoing knee arthroplasty for [osteoarthritis].

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Who should consider clinical trials for constriction, pathologic?

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Results from a recent paper represents the largest prospective analysis of clinical trials for constriction, pathologic in the medical literature. Results from a recent paper showed a high prevalence of constriction, pathologic, in patients with pancreatic cancer and suggests that these patients should be a high priority for clinical trials.

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What is the primary cause of constriction, pathologic?

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Secondary constrictions are commonly seen due to disease processes. However, the primary cause in approximately 15% of patients with constrictions remains unknown until the pathological study is done. The study is necessary to identify the cause of constriction and hopefully reduce subsequent complications.

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Does constriction, pathologic run in families?

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Most of these subjects may be construed as having concomitant disorders such as hyperprolactinemia and/or growth hormone deficiency. In general, the study findings do not support an association between constriction, pathologic run in families, and increased frequency of nonadventitial-type giant-cell lesions in the jaws of patients with familial gingival fibromatosis.

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Have there been other clinical trials involving spy fluorescent angiography?

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No clinical trials has been reported that has involved a comparison between SPECT-directed embolization and conventional angiography for the treatment of patients with varicose limb and its complications.

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How serious can constriction, pathologic be?

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There were very low rates of serious constriction by surgical repair. There was an elevated rate of minor constriction that had to be removed or closed. There was also an elevated risk of constriction rupture with this procedure. We believe that constriction repair is a safe, effective, and efficient technique to correct [constricting bands of tissue], especially of constricting bands in the [right ventricle of the heart when aortic root coarctation requires surgical correction].

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