This trial is evaluating whether ProProKera Plus® will improve 1 primary outcome and 8 secondary outcomes in patients with Corneal Ulcer. Measurement will happen over the course of up to 3 months after initial treatment.
This trial requires 24 total participants across 2 different treatment groups
This trial involves 2 different treatments. ProProKera Plus® is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The cause of ulceration remains a mystery. Factors like an increased acid load could not be fully ruled out. Some ulcers were still unexplained. Although the mechanism of ulcer formation remains to be determined, the overall increase in acid load in the stomach could result in more acid-related ulcerations in the future." - Anonymous Online Contributor
"Among US adults, 25,066 individuals experience an ulcer (bleeding/disfecation from ulcer) a year, making it the second most common cause of the hospitalization of patients with gastrointestinal symptoms. In all age groups, females are more likely to experience gastrointestinal ulcers than males, with the exception of 55+ year old women. Age-adjusted rates were about 3.4 per 100,000 inhabitants per year among females and 2.4 among males." - Anonymous Online Contributor
"A variety of ulcer treatment options are available. The most effective, durable treatment of choice is wound care with topical ulcer dressing and high-caloric diets." - Anonymous Online Contributor
"Ulcer is a common problem, and, despite medical intervention, half the patients required major surgical procedures and 3/5 will require ambulatory care to treat this condition." - Anonymous Online Contributor
"Ulcer seems to be a common disease affecting between one out of ten and one out of five people in the general population of Hong Kong. It commonly affects people during the age group of 40 to 60 years. The disease is most commonly due to injury, or malnutrition or infection resulting from lack of access to health care. Diagnosis of ulcer is generally by clinical observation and the use of specific laboratory tests." - Anonymous Online Contributor
"Based on the present data, the combination tested was well tolerated in clinical practice, and further studies are warranted to evaluate its efficacy in real-life settings." - Anonymous Online Contributor
"Findings from a recent study provides no evidence that ulcer is a dominantly inherited disease. Whether ulcer is a multifactorial disease is still a matter of debate." - Anonymous Online Contributor
"Since its introduction in 2007, proprokera plus® has been demonstrated to be effective for the improvement of skin roughness, roughness of hair growth and hair strength in subjects with photo-aged and/or dry skin. Proprokera+ plus® is considered one of the top three products that can be purchased online. It is now available through many commercial dealerships worldwide and has also been launched in countries around the world, including Brazil, Germany, Italy, Mexico, the Netherlands, Spain, Serbia and the United States. Its effectiveness is also well supported by the many published clinical studies, which have been carried out on thousands of different subjects." - Anonymous Online Contributor
"Ulcer incidence was found to be significantly higher in males than in females; however, the incidence was much lower in those with higher levels of education, but greater age and other factors were found to be significant risk factors for the disease in both genders." - Anonymous Online Contributor
"Ulcer and other gastrointestinal (GI) symptoms had the highest frequency associated with serious complications. Other features that increase risk for serious complications included: diabetes mellitus, smoking, and higher number of previous ulcer episodes. As serious complications in SES increased the mortality rate doubled, while the majority of cases remained in the outpatient setting, for non-life threatening condition." - Anonymous Online Contributor
"In a recent study, findings, all patients were treated for their severe dry dry skin with Proprokera. The most frequent adverse events included dry skin, dry scalp, and itching." - Anonymous Online Contributor