Written Exposure Therapy (WET) for Moral Injury

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
The University of Texas Health Science Center at San Antonio, San Antonio, TX
Moral Injury+2 More
Written Exposure Therapy (WET) - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

The primary objective of this study is to evaluate the safety, feasibility, and psychological and physiological treatment benefits of transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, when delivered in combination with Written Exposure Therapy (WET), for posttraumatic stress disorder posttraumatic stress disorder (PTSD).

Eligible Conditions

  • Moral Injury
  • Post Traumatic Stress Disorder (PTSD)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

3 Primary · 5 Secondary · Reporting Duration: Baseline to 9 weeks (one month post study treatment)

5 weeks
Number of subjects that completed all 5 WET sessions
Week 9
Clinician Administer PTSD Scale-5 (CAPS-5)
Depressive Symptom Index-Suicidality Subscale (DSI-SS)
Generalize Anxiety Disorder-7 (GAD)
Number of reported adverse events reported
Patient Health Questionnaire-9 (PHQ)
Posttraumatic Cognitions Inventory (PTCI)
Posttraumatic Stress Disorder Checklist (PCL-5)

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

tDCS plus WET
1 of 2
Sham plus WET
1 of 2
Experimental Treatment
Non-Treatment Group

40 Total Participants · 2 Treatment Groups

Primary Treatment: Written Exposure Therapy (WET) · Has Placebo Group · N/A

tDCS plus WETExperimental Group · 2 Interventions: Written Exposure Therapy (WET), Soterix 1x1 tDCS mini CT · Intervention Types: Behavioral, Device
Sham plus WETShamComparator Group · 2 Interventions: Written Exposure Therapy (WET), Sham Soterix 1x1 tDCS Mini CT · Intervention Types: Behavioral, Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 9 weeks (one month post study treatment)
Closest Location: The University of Texas Health Science Center at San Antonio · San Antonio, TX
Photo of San Antonio 1Photo of San Antonio 2Photo of San Antonio 3
2005First Recorded Clinical Trial
0 TrialsResearching Moral Injury
42 CompletedClinical Trials

Who is running the clinical trial?

The University of Texas Health Science Center at San AntonioLead Sponsor
388 Previous Clinical Trials
74,265 Total Patients Enrolled
Casey Straud, PsyDPrincipal InvestigatorUniversity of Texas Health Science Center San Antonio
1 Previous Clinical Trials
28 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are taking a stable psychotropic medication regimen for at least four weeks prior to the onset of study participation.
You have a PTSD diagnosis as assessed by the CAPS-5.
You are between the ages of 18 and 65 years old at time of screening.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.