Adenotonsillectomy for Obstructive Sleep Apnea

UCLA, Los Angeles, CA
AdenotonsillectomyN/ARecruitingResearch Sponsored by University of California, Los Angeles

Study Summary

This trial is examining the effects of sleep apnea on the brain in children.

Eligible Conditions
  • Pediatric Obstructive Sleep Apnea

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You are not taking any medications for brain disorders.
You don't have any known neurological conditions.
You are not currently receiving treatment for your breathing problem.
Only children who are in good health can participate.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Brain tissue changes between baseline and after adenotonsillectomy.
Cognition assessment after adenotonsillectomy in pediatric obstructive sleep apnea patients.
Cognitive symptoms examination after adenotonsillectomy surgery.
+3 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: 35 Pediatric Obstructive Sleep ApneaExperimental Treatment1 Intervention
The investigators will also determine whether brain tissue changes, reduced CBF, and altered neural responses to cognitive challenge reverse, and cognition and mood signs improve after standard surgical procedure "adenotonsillectomy" for breathing condition at 6 months in pediatric OSA.
First Studied
Drug Approval Stage
How many patients have taken this drug

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Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,467 Previous Clinical Trials
10,148,772 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total capacity of enrollees for this clinical investigation?

"Affirmative, states that this medical trial is actively enrolling participants. It was first uploaded on May 14th of 2022 and has since been revised as recently as June 29th. 70 individuals are sought to take part in the study at one single site."

Answered by AI

Are there any participants still needed for this experiment?

"The evidence from suggests that this investigation is presently recruiting patients, with the first posting occuring on May 14th 2022 and a subsequent update on June 29th 2022."

Answered by AI

Is this experiment looking to involve participants aged 45 and over?

"This trial has a lower age limit of 7, and an upper bound of 12. Consequently, minors aged between these two thresholds are eligible for enrolment."

Answered by AI

Do I qualify to participate in this experiment?

"This investigation is inviting 70 youths between seven and twelve years of age to participate. Applicants must possess a diagnosis of obstructive [sleep apnea]( (AHI > 5 events/hour) that was received from an overnight polysomnography at a sleep centre, be without obesity (BMI ≥ 95th percentile for their respective age and gender), not yet have any treatments for the breathing condition, agree to undergo adenotonsillectomy surgery, as well as meet all criteria regarding sex, BMI-matched control subjects aged 7-12 years with no more than ±3 months' difference in age."

Answered by AI

Who else is applying?

What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?

Why did patients apply to this trial?

Desperately need treatment for my sleep apnea disorder.
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~21 spots leftby Apr 2024