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Proximal Resistance Training for Multiple Sclerosis (PT-MS Trial)

N/A
Waitlist Available
Led By Mark M. Manago, DPT, PhD
Research Sponsored by University of Colorado, Denver
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
18-64 years old
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, end of 10 week intervention period, 22 week follow-up.
Awards & highlights

PT-MS Trial Summary

This trial is testing a new exercise intervention for people with MS. The goal is to see if it is feasible and if it improves walking function.

Eligible Conditions
  • Multiple Sclerosis

PT-MS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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You must be between 18 and 64 years old.

PT-MS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in 6-minute walk test
Secondary outcome measures
Change in Exercise Self-Efficacy Scale
Change in Exercise Stages of Change category
Change in Modified Fatigue Impact Scale
+4 more
Other outcome measures
25 Foot Walk Test
Change in Patient-Specific Functional Scale
Change in hip abduction strength
+3 more

PT-MS Trial Design

1Treatment groups
Experimental Treatment
Group I: Proximal Resistance TrainingExperimental Treatment1 Intervention
Participants will receive 6 one-on-one supervised intervention visits and 8 telerehabilitation visits over 10 weeks. For the first 4 weeks intervention frequency will start with 1x/ week in clinic and 1x/ week via telerehabilitation, and the participant will be asked to perform exercises 2x/ week independently. For the final 6 weeks there will be 1x week supervised visits (weeks 6 and 8 in person, and weeks 5,7, 9, and 10 via telerehabilitation) and the participant will be asked to perform exercises 3x/ week independently.

Find a Location

Who is running the clinical trial?

University of Colorado, DenverLead Sponsor
1,726 Previous Clinical Trials
2,141,642 Total Patients Enrolled
20 Trials studying Multiple Sclerosis
2,733 Patients Enrolled for Multiple Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,335 Previous Clinical Trials
648,497 Total Patients Enrolled
36 Trials studying Multiple Sclerosis
9,275 Patients Enrolled for Multiple Sclerosis
National Institutes of Health (NIH)NIH
2,681 Previous Clinical Trials
6,930,180 Total Patients Enrolled
9 Trials studying Multiple Sclerosis
1,286 Patients Enrolled for Multiple Sclerosis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~8 spots leftby Mar 2025