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Antipsychotic Drugs for Schizophrenia

N/A
Waitlist Available
Research Sponsored by National Center for Research Resources (NCRR)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Meet DSM-IV criteria for schizophrenia, any type, or schizoaffective disorder
No medication changes for 2 weeks prior to and during the period of study
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is comparing how two antipsychotic drugs affect levels of glucose and insulin in the body. People with schizophrenia are more likely to have problems with blood sugar regulation, and it's possible that antipsychotic drugs may make this worse.

Who is the study for?
This trial is for individuals with schizophrenia or schizoaffective disorder who are currently on olanzapine, risperidone, haloperidol, or another typical antipsychotic. They must not have had medication changes for two weeks before the study and be able to give informed consent.Check my eligibility
What is being tested?
The study examines how risperidone and olanzapine affect blood sugar control by influencing glucose and insulin levels in the body. It aims to understand if these medications contribute to diabetes risk in people with schizophrenia.See study design
What are the potential side effects?
Potential side effects may include changes in glucose regulation leading to increased risk of type 2 diabetes, weight gain, and possibly other metabolic complications associated with antipsychotic treatments.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been diagnosed with schizophrenia or schizoaffective disorder.
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I haven't changed my medications in the last 2 weeks and won't during the study.
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I am currently taking medications like olanzapine or risperidone.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

Washington University School of MedicineOTHER
1,928 Previous Clinical Trials
2,297,088 Total Patients Enrolled
16 Trials studying Schizophrenia
1,065 Patients Enrolled for Schizophrenia
Janssen, LPIndustry Sponsor
158 Previous Clinical Trials
304,958 Total Patients Enrolled
26 Trials studying Schizophrenia
7,156 Patients Enrolled for Schizophrenia
National Center for Research Resources (NCRR)Lead Sponsor
537 Previous Clinical Trials
317,016 Total Patients Enrolled

Media Library

Glucose Regulation (Other) Clinical Trial Eligibility Overview. Trial Name: NCT00006195 — N/A
Schizophrenia Research Study Groups:
Schizophrenia Clinical Trial 2023: Glucose Regulation Highlights & Side Effects. Trial Name: NCT00006195 — N/A
Glucose Regulation (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00006195 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the elderly population being considered for participation in this experiment?

"Patients aged 18 to 60 are eligible for this trial, while individuals younger than that should consider the 46 studies specifically designed for them. Meanwhile, those older than 65 may be interested in looking at the 164 trials tailored to their age group."

Answered by AI
~233 spots leftby Mar 2025