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Non-Pharmacological Therapy

Transcranial Direct Current Stimulation for Schizophrenia

N/A
Waitlist Available
Research Sponsored by University of California, Davis
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of schizophrenia, schizophreniform or schizoaffective disorder (for patient group)
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up assessment will begin immediately following stimulation and last for up to an hour.
Awards & highlights

Study Summary

This trial is testing whether transcranial direct current stimulation (tDCS) can help people with schizophrenia better understand and use cognitive control, a process that is essential for goal-directed behavior. tDCS is a noninvasive method of applying a weak electrical current to the brain. The study will also use functional magnetic resonance imaging (fMRI) to examine the effects of tDCS on the neuronal mechanisms of cognitive control in schizophrenia.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have been diagnosed with schizophrenia, schizophreniform disorder, or schizoaffective disorder.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~assessment will begin immediately following stimulation and last for up to an hour.
This trial's timeline: 3 weeks for screening, Varies for treatment, and assessment will begin immediately following stimulation and last for up to an hour. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Behavioral Response
Dorsolateral Prefrontal Cortex Response

Side effects data

From 2021 Phase 2 & 3 trial • 160 Patients • NCT02483468
2%
skin irritation
2%
Car accident
100%
80%
60%
40%
20%
0%
Study treatment Arm
tDCS (Active)
tDCS (Sham)

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Experimental StimulationExperimental Treatment1 Intervention
Intervention. 20 minutes of 2 mA direct current stimulation over the dorsolateral prefrontal cortex
Group II: Sham StimulationPlacebo Group1 Intervention
Placebo Comparator. 0.5-1 minutes of 2 mA direct current stimulation over the dorsolateral prefrontal cortex followed by 19-19.5 minutes of sham stimulation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Direct Current Stimulation
2014
Completed Phase 3
~1100

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor
908 Previous Clinical Trials
4,704,109 Total Patients Enrolled
3 Trials studying Schizophrenia
295 Patients Enrolled for Schizophrenia
Cameron Carter, M.D.Study DirectorUniversity of California, Davis

Media Library

tDCS (Non-Pharmacological Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT03077347 — N/A
Schizophrenia Research Study Groups: Experimental Stimulation, Sham Stimulation
Schizophrenia Clinical Trial 2023: tDCS Highlights & Side Effects. Trial Name: NCT03077347 — N/A
tDCS (Non-Pharmacological Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03077347 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the enrollment criteria encompass individuals up to age 80?

"The enrollment requirements for this trial necessitate that participants are at least 18 and not beyond 35 years of age."

Answered by AI

What is the enrollment capacity of this clinical trial?

"Affirmative. The information available on clinicaltrials.gov states that the research is still recruiting patients, having initially been posted on April 1st 2017 and last updated August 3rd 2022. This study seeks to recruit 100 participants from a single medical site."

Answered by AI

Could I potentially qualify for this research endeavor?

"This clinical trial seeks 100 young individuals aged 18 to 35 who suffer from schizophrenia, schizophreniform disorder, or schizoaffective disorder. To be considered for this study, a participant must possess adequate English literacy in order to understand and complete assigned tasks; they should also have the legal capacity to issue valid informed consent. Additionally, all participants need to maintain stable outpatient or partial hospital status throughout the course of the experiment."

Answered by AI

Is participation in this clinical trial available to the public at present?

"The investigation, which was initially posted on April 1st 2017 and modified most recently on August 3rd 2022, is actively searching for participants according to clinicaltrials.gov."

Answered by AI

Who else is applying?

What state do they live in?
Illinois
How old are they?
18 - 65
What site did they apply to?
Imaging Research Center, University of California Davis Medical Center
What portion of applicants met pre-screening criteria?
Did not meet criteria
~1 spots leftby Mar 2025