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Genetic Analysis for Schizophrenia

N/A
Recruiting
Led By Herbert Y Meltzer, M.D.
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients with the diagnoses of schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features, or volunteers with no history of a psychotic disorder.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up single visit
Awards & highlights

Study Summary

This trial aims to find out if certain genes can predict how well a person will respond to the antipsychotic drug, clozapine.

Eligible Conditions
  • Schizophrenia
  • Schizoaffective Disorder
  • Depression
  • Bipolar Disorder

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You cannot participate if you have been diagnosed with certain mental health conditions such as schizophrenia, schizoaffective disorder or bipolar disorder with psychotic features.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~single visit
This trial's timeline: 3 weeks for screening, Varies for treatment, and single visit for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
We plan to compare the polymorphisms across schizophrenic patients and adults who do not have a diagnosed major mental illness. .
Secondary outcome measures
We will also evaluate relationships between the polymorphism and past and current mental health among the non-diagnosed sample

Trial Design

2Treatment groups
Active Control
Group I: 1 Outcome in schizophrenia with certain antipsychoticActive Control2 Interventions
clozapine
Group II: 2 Outcome in schizophrenia with other AntipsychoticsActive Control2 Interventions
Other Antipsychotics

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,576 Previous Clinical Trials
910,922 Total Patients Enrolled
11 Trials studying Schizophrenia
1,145 Patients Enrolled for Schizophrenia
Vanderbilt UniversityLead Sponsor
702 Previous Clinical Trials
6,141,769 Total Patients Enrolled
9 Trials studying Schizophrenia
855 Patients Enrolled for Schizophrenia
Herbert Y Meltzer, M.D.Principal InvestigatorVanderbilt University Medical Center
4 Previous Clinical Trials
510 Total Patients Enrolled
4 Trials studying Schizophrenia
510 Patients Enrolled for Schizophrenia

Media Library

1 Outcome in schizophrenia with certain antipsychotic Clinical Trial Eligibility Overview. Trial Name: NCT00178932 — N/A
Schizophrenia Research Study Groups: 1 Outcome in schizophrenia with certain antipsychotic, 2 Outcome in schizophrenia with other Antipsychotics
Schizophrenia Clinical Trial 2023: 1 Outcome in schizophrenia with certain antipsychotic Highlights & Side Effects. Trial Name: NCT00178932 — N/A
1 Outcome in schizophrenia with certain antipsychotic 2023 Treatment Timeline for Medical Study. Trial Name: NCT00178932 — N/A
Schizophrenia Patient Testimony for trial: Trial Name: NCT00178932 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any restrictions on who can volunteer for this research project?

"This medical investigation requires 1000 participants with manic disorder to be recruited, each of whom must fall within the 18-65 age bracket."

Answered by AI

Are new participants able to enlist in this experiment?

"According to the details attained from clinicaltrials.gov, this study is actively searching for participants. It was first posted on November 1st 1998 and most recently updated April 11th 2022."

Answered by AI

Does the trial allow adults under 30 to participate?

"This trial is open for patients aged between 18 and 65. If a patient falls outside of this range, there are 345 trials targeting younger individuals and 990 studies recruiting elderly people."

Answered by AI

How many participants is this experiment accommodating?

"Affirmative. Clinicaltrials.gov contains evidence that this study is actively enrolling patients since its inception on November 1st 1998 and latest update on April 11th 2022, with the goal of recruiting one thousand participants at a singular trial site."

Answered by AI

Who else is applying?

What state do they live in?
Kentucky
What site did they apply to?
Psychiatric Hospital at Vanderbilt
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+

What questions have other patients asked about this trial?

How Much do I get paid and How many trips will I have to make to Nashville?
PatientReceived 1 prior treatment

Why did patients apply to this trial?

Because I have been on many medication for my mood swings, me not wanting to be around people and my past drug usage. I'm willing to try something else because if it helps me, it could help a lot of people with what goes threw my mind.
PatientReceived 2+ prior treatments
~38 spots leftby Mar 2025