← Back to Search

AutoTutor (PsyGist) for Psychosis

Phase 1
Waitlist Available
Led By Lawrence Yang, PhD
Research Sponsored by New York University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Current or previous COPE participant
Identified as at clinical high risk for psychosis as defined as having at least one of the following: a)attenuated positive symptoms b)brief intermittent positive symptoms
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 15 minutes
Awards & highlights

Study Summary

This trial aims to develop two clinical tools to help high-risk youth make healthy choices by using a genetic malleability framing.

Eligible Conditions
  • Psychosis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~15 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 15 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Behavioral Measure for Intent to Engage in Treatment
Increased Intent to Engage in Treatment and Healthy Behaviors
Secondary outcome measures
Anticipated Discrimination from Others Due to Genetic Risk for Psychosis Development
Anticipated Rejection from Others Due to Genetic Risk for Psychosis Development
Implicit Association Test
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Clinician ManualExperimental Treatment1 Intervention
Participants in the Clinician Manual arm will be introduced to a trained clinician and will complete one 60-minute session covering equivalent topics addressed in the PsyGist program. The manual will consist of: (1) a section exploring the youth's causal model for their high-risk state; (2) individualization per their causal model; and (3) tutorials that convey the main concepts of genetic malleability. Clinicians will assess individual causal models via discussion with CHR youth about their at- risk state. Individualization of genetic framing will occur using youths' causal models and will fall into 1 of 3 categories (per PsyGist): 'primarily genetic', 'primarily environmental' or 'combined'.
Group II: AutoTutor (PsyGist)Experimental Treatment1 Intervention
AutoTutor is an intelligent system that simulates talking with a human tutor. Our AutoTutor, called PsyGist, has 3 parts: (1) assessment of the youth's causal model for their high-risk state; (2) an individualized 'pre-tutorial' vignette matched to their causal model; (3) a 'tutorial' presenting the 'genetic malleability' framing. PsyGist will guide participants through its three components.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
PsyGist and Clinician Manual
2020
Completed Phase 1
~30

Find a Location

Who is running the clinical trial?

New York State Psychiatric InstituteOTHER
474 Previous Clinical Trials
153,232 Total Patients Enrolled
7 Trials studying Psychosis
950 Patients Enrolled for Psychosis
New York UniversityLead Sponsor
224 Previous Clinical Trials
311,960 Total Patients Enrolled
2 Trials studying Psychosis
424 Patients Enrolled for Psychosis
Lawrence Yang, PhDPrincipal InvestigatorNew York University
1 Previous Clinical Trials
360 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the criteria to participate in this experiment?

"This clinical research is recruiting 54 individuals aged 16-30 who currently have psychosis and fit into one of the three categories listed under atteneded positive symptoms. Furthermore, all interested candidates must be (or recently had been) participants in COPE."

Answered by AI

Does the inclusion criteria for this research project include those aged sixty and above?

"This clinical study has particular requirements for qualified applicants; they must be between 16 and 30 years old. There are 116 trials specifically recruiting minors and 262 trials that cater to elderly patients."

Answered by AI

What is the targeted cohort for this clinical research?

"Affirmative. The clinical trial website, clinicaltrials.gov, reports that the research is actively recruiting with 54 patients needing to be recruited from one medical centre. This study was first posted on November 16th 2020 and most recently updated June 6th 2022."

Answered by AI

Is the research team actively seeking participants for this experiment?

"As confirmed by clinicaltrials.gov, this medical trial is actively in search of participants. The initial post was on the 16th November 2020 and it has since been revised at least once as of 6 June 2022."

Answered by AI

What aims has this trial been designed to achieve?

"The primary focus of this 15-minute clinical trial is to measure Behavioral Intent towards Engaging in Treatment. Secondary outcomes include Anticipated Rejection and Discrimination from Others Due to Genetic Risk for Psychosis Development, which are both based on published scales (Link et al., 2015; Wahl, 1999). Additionally, an Implicit Association Test will be performed to assess participants' associations between 'Normal/Abnormal' and 'Changeable/Permanent'. As it is an exploratory R21 study, the investigators have constructed new measures as well."

Answered by AI
~6 spots leftby Mar 2025