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Narrow Band Phototherapy for Psoriasis (LITE Trial)
LITE Trial Summary
This trial compares home-based versus office-based UVB phototherapy for psoriasis. It will look at effectiveness, safety, and duration of response at 12 weeks.
- Psoriasis
LITE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowLITE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.LITE Trial Design
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Who is running the clinical trial?
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- You have tried light therapy before but it didn't work for you, or you received light therapy in the 14 days leading up to the study.You have psoriasis on your body and it's mainly on your trunk and/or limbs. Your doctor thinks you could benefit from phototherapy.You have psoriasis mainly on your torso and limbs, and your doctor thinks you may benefit from phototherapy.You have psoriasis on your trunk and/or extremities that is considered a good fit for phototherapy treatment, and has a physician-assessed severity level of more than 1.0.You are 12 years old or older.You have psoriasis mainly on your scalp, body folds, genitals, palms, or soles. Your overall assessment by a doctor is mild or better.
- Group 1: Office Based Phototherapy
- Group 2: Home Based Phototherapy
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What potential outcomes is this research aiming to realize?
"The core measurement of success for this trial is the impact that dermatological disease has on quality of life, assessed over a time period of 12 weeks or when phototherapy ceases. Secondary objectives include tracking data related to phototherapy dosing and patient-reported costs associated with travelling for treatments."
How many participants are there for this experiment?
"Yes, according to the records on clinicaltrials.gov this trial is in progress and actively seeking participants. The research was posted for the first time on March 1st 2019 and has been edited most recently on August 16th 2022. It aims to recruit 1050 individuals from 40 different sites."
Are there any unfilled opportunities for participants in this investigation?
"Affirmative. Clinicaltrials.gov shows that this clinical trial, which was first advertised on March 1st 2019, is currently recruiting patients. Approximately 1050 volunteers need to be recruited from 40 locations."
How many healthcare institutions are currently engaged in this research endeavor?
"Currently, 40 medical centres across the USA are conducting this study. Of these, 3 locations are in Brooklyn, Dallas and Madison while all other sites can be located via a map or web search. To reduce travel time for participants it is suggested to choose the nearest site to join this trial."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
How responsive is this trial?
Most responsive sites:
- Dermatology Treatment and Research Center: < 48 hours
- Dawes Fretzin Clinical Research: < 48 hours
Typically responds via
Average response time
- < 2 Days
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