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Phototherapy

Narrow Band Phototherapy for Psoriasis (LITE Trial)

N/A
Waitlist Available
Led By Joel M. Gelfand, MD,MSCE
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Plaque or guttate psoriasis predominantly located on trunk and/or extremities, with a physician global assessment average of >1.0, and considered a candidate for phototherapy
Plaque or guttate psoriasis predominantly located on trunk and/or extremities, with a physician global assessment average of >1.0, and considered a candidate for phototherapy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks after randomization or earlier at discontinuation of phototherapy
Awards & highlights

LITE Trial Summary

This trial compares home-based versus office-based UVB phototherapy for psoriasis. It will look at effectiveness, safety, and duration of response at 12 weeks.

Eligible Conditions
  • Psoriasis

LITE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have psoriasis on your trunk and/or extremities that is considered a good fit for phototherapy treatment, and has a physician-assessed severity level of more than 1.0.
Select...
You have psoriasis mainly on your torso and limbs, and your doctor thinks you may benefit from phototherapy.

LITE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks after randomization or earlier at discontinuation of phototherapy
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks after randomization or earlier at discontinuation of phototherapy for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Impact of dermatological disease on quality of life
Treatment Response
Secondary outcome measures
Body Surface Area multiplied by Physician Global Assessment
Concomitant topical psoriasis treatment
Duration of treatment response during observation period
+4 more

LITE Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Office Based PhototherapyExperimental Treatment1 Intervention
Patients randomized to this arm will receive narrow band phototherapy in a clinical setting via narrow band phototherapy clinic units.
Group II: Home Based PhototherapyActive Control1 Intervention
Patients randomized to this arm will receive narrow band phototherapy in a home setting via Daavlin 7 series 3 panel narrow band phototherapy home units.

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
1,991 Previous Clinical Trials
42,874,730 Total Patients Enrolled
11 Trials studying Psoriasis
2,015 Patients Enrolled for Psoriasis
University of UtahOTHER
1,088 Previous Clinical Trials
1,727,299 Total Patients Enrolled
2 Trials studying Psoriasis
21 Patients Enrolled for Psoriasis
National Psoriasis FoundationOTHER
11 Previous Clinical Trials
1,099 Total Patients Enrolled
10 Trials studying Psoriasis
1,077 Patients Enrolled for Psoriasis

Media Library

Daavlin 7 series 3 panel narrow band phototherapy home units (Phototherapy) Clinical Trial Eligibility Overview. Trial Name: NCT03726489 — N/A
Psoriasis Research Study Groups: Office Based Phototherapy, Home Based Phototherapy
Psoriasis Clinical Trial 2023: Daavlin 7 series 3 panel narrow band phototherapy home units Highlights & Side Effects. Trial Name: NCT03726489 — N/A
Daavlin 7 series 3 panel narrow band phototherapy home units (Phototherapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03726489 — N/A
Psoriasis Patient Testimony for trial: Trial Name: NCT03726489 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential outcomes is this research aiming to realize?

"The core measurement of success for this trial is the impact that dermatological disease has on quality of life, assessed over a time period of 12 weeks or when phototherapy ceases. Secondary objectives include tracking data related to phototherapy dosing and patient-reported costs associated with travelling for treatments."

Answered by AI

How many participants are there for this experiment?

"Yes, according to the records on clinicaltrials.gov this trial is in progress and actively seeking participants. The research was posted for the first time on March 1st 2019 and has been edited most recently on August 16th 2022. It aims to recruit 1050 individuals from 40 different sites."

Answered by AI

Are there any unfilled opportunities for participants in this investigation?

"Affirmative. Clinicaltrials.gov shows that this clinical trial, which was first advertised on March 1st 2019, is currently recruiting patients. Approximately 1050 volunteers need to be recruited from 40 locations."

Answered by AI

How many healthcare institutions are currently engaged in this research endeavor?

"Currently, 40 medical centres across the USA are conducting this study. Of these, 3 locations are in Brooklyn, Dallas and Madison while all other sites can be located via a map or web search. To reduce travel time for participants it is suggested to choose the nearest site to join this trial."

Answered by AI

Who else is applying?

What state do they live in?
New York
Indiana
Other
Texas
How old are they?
18 - 65
What site did they apply to?
Mayo Clinic Arizona
Dawes Fretzin Clinical Research
Infinity Dermatology NYC
Other
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
2
3+

Why did patients apply to this trial?

I have Plaque psoriasis but only on my head. Figured I would try a clinical study.
PatientReceived 2+ prior treatments
I suffered as a child with it went into remission when I started menstrual cycle. I'm post menopausal it has returned with a vengeance from my scalp to my feet.I don't have health care and willing to do anything to help me and this disease.
PatientReceived 2+ prior treatments

How responsive is this trial?

Most responsive sites:
  1. Dermatology Treatment and Research Center: < 48 hours
  2. Dawes Fretzin Clinical Research: < 48 hours
Typically responds via
Phone Call
Average response time
  • < 2 Days
~175 spots leftby Mar 2025