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Behavioural Intervention

Genetic Counseling Methods for Prostate Cancer (ProGen Trial)

N/A
Waitlist Available
Led By Huma Q Rana, MD
Research Sponsored by Dana-Farber Cancer Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Prostate cancer and a personal history of prior malignancy that does not include non-melanoma skin cancer or superficial bladder cancer
Prostate cancer diagnosis (any grade/stage) or prostate biopsy with high grade PIN or small acinar proliferation and a family history potentially indicating a germline mutation (e.g. breast cancer diagnosed at age ≤ 50, ovarian, pancreatic, uterine, colorectal, prostate cancer or sarcoma, in one or more first or second-degree relatives)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

ProGen Trial Summary

This trial is testing whether pre-test video education and post-test genetic counseling is as effective as in-person pre-test genetic counseling for males with advanced prostate cancer.

Eligible Conditions
  • Prostate Cancer

ProGen Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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You have prostate cancer and have had a previous cancer, except for non-melanoma skin cancer or superficial bladder cancer.
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You have been diagnosed with prostate cancer or have a family history of certain cancers that may indicate a genetic mutation.

ProGen Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Prevalence of germline mutations in males with prostate cancer
Secondary outcome measures
Family communication for those who tested positive for a genetic mutation
Genetic testing satisfaction score
Genetic testing uptake
+4 more

ProGen Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Pre-test video educationExperimental Treatment1 Intervention
Participant is given a pamphlet that describes the basics of prostate cancer genes, genetic testing Participant is sent electronic family history tool Participant is approached in clinic by research staff at a pre-planned time The patient is given the "Genetic Testing Information for Decision Making" packet The pre-test video education is a short video. Information will be provided about the basics of genetics and mutations, the potential benefits, risks, and limitations of genetic testing, and the possible results the participant may receive
Group II: Traditional pre-test genetic counselingActive Control1 Intervention
In-person consultation with licensed genetic counselor at the Center for Cancer Genetics and Prevention before genetic testing Participant is given a pamphlet introducing prostate cancer genes, genetic testing Participant is sent electronic family history tool Participant is given the "Genetic Testing Information for Decision Making" packet. After the genetic counseling session, patient is asked if they would like to proceed with genetic testing.

Find a Location

Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor
1,071 Previous Clinical Trials
339,702 Total Patients Enrolled
76 Trials studying Prostate Cancer
15,453 Patients Enrolled for Prostate Cancer
University of Texas Southwestern Medical CenterOTHER
1,038 Previous Clinical Trials
1,046,109 Total Patients Enrolled
15 Trials studying Prostate Cancer
1,473 Patients Enrolled for Prostate Cancer
Barbara Ann Karmanos Cancer InstituteOTHER
163 Previous Clinical Trials
8,607 Total Patients Enrolled
14 Trials studying Prostate Cancer
409 Patients Enrolled for Prostate Cancer

Media Library

Pre-test video education (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT03328091 — N/A
Prostate Cancer Research Study Groups: Pre-test video education, Traditional pre-test genetic counseling
Prostate Cancer Clinical Trial 2023: Pre-test video education Highlights & Side Effects. Trial Name: NCT03328091 — N/A
Pre-test video education (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03328091 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research program taking on new subjects?

"According to clinicaltrials.gov, this medical trial is no longer accepting new patients; the first post was made on November 21st 2017 and it was most recently updated January 17th 2022. Nevertheless, there are still 1321 active trials searching for participants at present."

Answered by AI
~90 spots leftby Mar 2025