Intervention for Hypertension

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Hypertension+1 More
Intervention - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing a new sedentary behavior intervention to see if it can lower blood pressure in adults. The primary outcome is resting systolic blood pressure (SBP) at 3 months.

Eligible Conditions
  • Hypertension
  • Prehypertension

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: 3 months

3 months
24-hour Ambulatory Blood Pressure
Aldosterone
Diastolic Blood Pressure
Glucose
Insulin
Plasma Renin Activity
Pulse Wave Velocity
Resting Systolic Blood Pressure
Weight
Adverse events will be measured in an ongoing fashion (as reported) and formally at the 3-month outcome assessment by blinded personnel in all participants.
Adverse Events

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Control
1 of 2
Intervention
1 of 2

Active Control

Experimental Treatment

300 Total Participants · 2 Treatment Groups

Primary Treatment: Intervention · No Placebo Group · N/A

Intervention
Behavioral
Experimental Group · 1 Intervention: Intervention · Intervention Types: Behavioral
ControlNoIntervention Group · 1 Intervention: Control · Intervention Types:
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Intervention
2011
Completed Phase 4
~73850

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 months

Who is running the clinical trial?

National Heart, Lung, and Blood Institute (NHLBI)NIH
3,580 Previous Clinical Trials
46,968,696 Total Patients Enrolled
440 Trials studying Hypertension
2,121,530 Patients Enrolled for Hypertension
University of PittsburghLead Sponsor
1,601 Previous Clinical Trials
6,286,024 Total Patients Enrolled
28 Trials studying Hypertension
47,578 Patients Enrolled for Hypertension
Bethany Barone Gibbs, PhDPrincipal Investigator - University of Pittsburgh
University of Pittsburgh
3 Previous Clinical Trials
658 Total Patients Enrolled
1 Trials studying Hypertension
120 Patients Enrolled for Hypertension

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are currently doing deskwork for 20 hours or more per week at a desk compatible with the sit-stand attachment.
You are employed within an approximate 25-mile radius of the University of Pittsburgh.
You are employed and planning to stay employed for at least 3 months.
You possess a cellular phone able to receive text messages.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 4th, 2021

Last Reviewed: November 7th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.