Mobile Health Program for High Blood Pressure After Preeclampsia

SB
AT
Overseen ByAmy Travis
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: University of Pittsburgh
Must be taking: Antihypertensives
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Strategies targeted to optimize hypertension (HTN) control for midlife women after hypertensive disorders of pregnancy (HDP) have not been studied, despite evidence of a critical need. This proposal targets the 10-20 years postpartum as a key time when women have subclinical cardiovascular (CV) sequelae of uncontrolled HTN and are primed for CV prevention interventions. Before proceeding with large-scale intervention trials of a home blood pressure monitoring (HBPM) and coaching intervention following HDP, further pilot testing is necessary. The overarching hypothesis of this proposal is that a new monitoring and treatment paradigm utilizing HBPM combined with a virtual coaching intervention would be better than standard of care for mid-life women with prior HDP who develop HTN. Women will be assigned in an unblinded manner to the intervention or standard of care control group.

Who Is on the Research Team?

MC

Malamo Countouris, MD, MS

Principal Investigator

University of Pittsburgh

Are You a Good Fit for This Trial?

This trial is for women in midlife who had high blood pressure during pregnancy (like preeclampsia) and now have high blood pressure again, 10-20 years after giving birth. Participants should not have other major health issues that would prevent them from joining.

Inclusion Criteria

Women with a history of HDP (gestational HTN or preeclampsia) diagnosed by ACOG guidelines at delivery at Magee-Womens Hospital between 2008 and 2015, 10 to 20 years from their index pregnancy complicated by HDP
I currently have high blood pressure at or above 140/90 mmHg.

Exclusion Criteria

I gave birth 10 to 20 years ago and am not a child.
I have a history of heart or blood vessel disease.
I am not male.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive a smartphone-based, interactive coaching application and a Bluetooth blood pressure cuff for home-based blood pressure monitoring over a 3-month period

3 months
Virtual coaching sessions

Follow-up

Participants are monitored for changes in blood pressure and adherence to antihypertensive medications

3 months

Extended Follow-up

Participants continue to be monitored for blood pressure changes and medication adherence up to 6 months

3 months

What Are the Treatments Tested in This Trial?

Interventions

  • Coaching application
  • Home-based blood pressure monitoring

Trial Overview

The study compares a new program using home blood pressure monitoring with a coaching app (including WebMD resources) to usual care. Women are randomly assigned to either the new program or standard care to see which helps control blood pressure better.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Coaching Application + HBPMExperimental Treatment2 Interventions
Group II: Enhanced usual care with WebMDActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pittsburgh

Lead Sponsor

Trials
1,820
Recruited
16,360,000+

McKamish Family Foundation

Collaborator