CLINICAL TRIAL

CBT for parasomnias (CBT-p) for Parasomnias

Recruiting · 18+ · All Sexes · Winnipeg, Canada

This study is evaluating whether cognitive behavioral therapy can reduce parasomnias in people with sleep disorders.

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About the trial for Parasomnias

Eligible Conditions
Parasomnias · Sleep Wake Disorders · Parasomnia

Treatment Groups

This trial involves 2 different treatments. CBT For Parasomnias (CBT-p) is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
CBT for parasomnias (CBT-p)
BEHAVIORAL
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.
Self-Monitoring
BEHAVIORAL

Eligibility

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
At least one sleep disorder event per week. show original
Daytime fatigue or sleepiness can be a sign of a sleep disorder show original
The DSM 5 includes parasomnia disorder as a recognized condition show original
6 months in duration
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 6 weeks
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 6 weeks.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether CBT for parasomnias (CBT-p) will improve 3 primary outcomes and 6 secondary outcomes in patients with Parasomnias. Measurement will happen over the course of 6 weeks.

Impairment
6 WEEKS
Work and Social Adjustment Scale, 0-40, higher scores mean more impairment
Cognitive
6 WEEKS
PROMIS Applied Cognition Scale, 4-20, with higher scores meaning better cognition
Insomnia
6 WEEKS
Insomnia Severity Index, 0-28, with higher scores meaning more insomnia
Sleepiness
6 WEEKS
Epworth Sleepiness Scale, 0-24, higher scores mean more sleepiness
Depression, Anxiety, and Stress
6 WEEKS
Depression, Anxiety, and Stress Scale, o-63, with higher scores meaning more depression, anxiety, and stress
Fatigue
6 WEEKS
Multi-Dimensional Fatigue Inventory, 0-16, higher scores mean more fatigue
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Who is running the study

Principal Investigator
D. N. V.
Prof. Dr. Nora Vincent, MD
University of Manitoba

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for parasomnias?

The lack of quality evidence limits the choices of treatments in this area. Most trials have low methodological quality. Few trials provide the results to allow reliable comparisons of different treatments; in such cases comparisons are possible only between treatments without regard to whether the groups were representative of patients in a practice. It is likely that some treatments will be shown to be more effective than others based on their frequency of use; for this reason there is no good evidence as to which treatment is most effective.

Anonymous Patient Answer

Can parasomnias be cured?

There is evidence that many parasomnias, often as a result of psychiatric or other chronic disease, persist irrespective of treatment. The evidence for the use of the anticonvulsant carbamazepine is less convincing and needs further study.

Anonymous Patient Answer

What causes parasomnias?

A wide range of potential etiologies can cause parasomnias, ranging from physiological causes (e.g., hyperthyroidism, hypoxic deprivation) to psychological and psychiatric conditions: e.g., anxiety, major depressive disorder, panic disorder, and social phobia. Given that no cure for parasomnias is known, the focus for treatment is on relieving symptoms, addressing triggers, and managing secondary comorbidities. Psychological counseling is also very helpful. Furthermore, most children with behavioral disorders respond well to psychotherapy and/or medication.

Anonymous Patient Answer

What is parasomnias?

In patients who have suffered a traumatic brain injury (TBI), the most common presenting complaint is somnolence. One third of patients with TBI complain of excessive sleepiness and more than one-third reported trouble falling asleep. This suggests that sleep disorders are frequent in traumatic brain injury, and the differential evaluation may help determine a patient's postconcussion syndrome.

Anonymous Patient Answer

How many people get parasomnias a year in the United States?

About 2 million people are currently or previously diagnosed as having idiopathic paroxysmal hyperkinesia. Paroxysmal hyperkinesia is often associated with other behavioral/organic disorders and is usually not associated with psychiatric disorders. If this is the case, patients will seek medical attention for idiopathic paroxysmal hyperkinesia.

Anonymous Patient Answer

What are the signs of parasomnias?

The most common indications are sleep-related behaviours such as snoring, day-time sleepiness, sleep restriction, nocturnal awakenings, sleep terrors and nocturnal enuresis. The prevalence of snoring increases during adolescence, and sleep terrors peak at the age of 25-30 years.

Anonymous Patient Answer

Does parasomnias run in families?

The prevalence of sleep-related parasomnias in the family appears to be similar in healthy and non-healthy first-degree relatives of a patient with somnolence of excessive arousal (SUEA, EDS or hypersomnia), suggesting a genetic component in some families. SUEA is more common in families of sleep onset insomnia patients than in families of EDS patients, suggesting that an alteration of vigilance circadian phase is more likely to occur in the familial environment of EDS patients, than in the familial environment of SUEA patients. The presence of parasomnias has also been associated with a familial trait related to daytime somnolence, namely insomnia nocturnal awakenings or nighttime sleep complaints.

Anonymous Patient Answer

Have there been other clinical trials involving cbt for parasomnias (cbt-p)?

In view of the modest number of patients included in cbt-p, further studies involving larger numbers of patients must be encouraged. However, we have found some interesting aspects of the drug: firstly, it seems effective. Secondly, it may be used with some degree of security with an advantage over hypnotics, which in turn may not be at all effective.

Anonymous Patient Answer

How does cbt for parasomnias (cbt-p) work?

Findings from a recent study found that CBT-p is efficacious in treating sleep and sleep-related symptoms in children for a variety of severities of CPS. Sleep specialists should therefore incorporate CBT-p therapy along with other behavioral, medical, or pharmacological treatment approaches. In children and adolescents, long-term effectiveness for treatment with CBT was determined with minimal residual symptoms at posttreatment. Thus, CBT may be an important treatment avenue for CPS, and future longitudinal studies would be useful to determine CBT's long-term effectiveness.

Anonymous Patient Answer

What are the common side effects of cbt for parasomnias (cbt-p)?

The main side effect of cbt-p is insomnia and sleepiness at bed time and early morning awakening, sleepiness and a lower quality of sleep in general in the daytime. Other common side effects include dizziness, headache, nausea, constipation, vomiting, rash, urinary urgency and increased appetite.

Anonymous Patient Answer

What is the average age someone gets parasomnias?

Parasymnia symptoms occur widely in older patients. One of the most useful tools for the identification of syndromal causes of parasomnias is the assessment of sleep arousal, which can help differentiating among a large number of clinical and pathologic potential causes. If symptoms persist over a period of months to years, it is unlikely to be related to an actual organic cause, and treatment should be directed toward symptomatic treatment with medications most likely to disrupt sleep and sleep apnea-like events, such as a beta1-adrenergic agonist.

Anonymous Patient Answer

What is the latest research for parasomnias?

The most recent, relevant research suggests that sleep disorders may contribute to the development of parasomnias. Studies have failed to replicate the presence of sleep terrors, but more recent research suggests that other parasomnias, including night terror and sleep-related movement disorders, may be related. It remains unclear whether the relationship between sleep disorders and parasomnias is the result of sleep apnea or other undiagnosed sleep disorders. There is also still a lack of evidence pertaining to the link between sleep disorders and daytime sleep behaviours. Further research, using prospective and longitudinal studies, is needed to elucidate the causal pathway underlying these diverse associations.

Anonymous Patient Answer
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