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5-fluorouracil for Pancreatic Cancer

N/A
Waitlist Available
Research Sponsored by AHS Cancer Control Alberta
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up post treatment, patients will be followed every 3 months via phone call and/or electronic health record
Awards & highlights

Study Summary

Chemotherapy is given after curative surgery for pancreas cancer to try to improve cure rates. There are two choices of chemotherapy which are currently considered equal treatments: gemcitabine or 5-fluorouracil (5FU). This study is trying to determine if one of two standard chemotherapies is better than the other depending on whether patients have high or low human equilibrative nucleoside transporter 1 (hENT1). hENT1 is a protein that is found in varying amounts on pancreas cancers.

Eligible Conditions
  • Pancreatic Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~post treatment, patients will be followed every 3 months via phone call and/or electronic health record
This trial's timeline: 3 weeks for screening, Varies for treatment, and post treatment, patients will be followed every 3 months via phone call and/or electronic health record for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Overall Survival

Trial Design

2Treatment groups
Experimental Treatment
Group I: GemcitabineExperimental Treatment1 Intervention
Group II: 5-fluorouracilExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Gemcitabine
FDA approved
Fluorouracil
FDA approved

Find a Location

Who is running the clinical trial?

AHS Cancer Control AlbertaLead Sponsor
182 Previous Clinical Trials
36,192 Total Patients Enrolled
Jennifer Spratlin, MD, FRCPCStudy ChairCross Cancer Institute

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Biomarker Directed Adjuvant Chemotherapy for Resected Pancreas Cancer
2011. "Biomarker Directed Adjuvant Chemotherapy for Resected Pancreas Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01411072.
All > Pancreas Cancer > Cte
~1 spots leftby Apr 2025
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