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Pain Informed Movement for Osteoarthritis

N/A
Waitlist Available
Led By Lisa Carlesso, PhD
Research Sponsored by McMaster University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
40 years of age and over
Have a diagnosis of knee OA by a physician
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

Study Summary

The pain experience and its associated mechanisms in people with knee osteoarthritis (OA) are known to be complex and multidimensional. The current understanding of OA pain mechanisms is incomplete, resulting in limited pain management strategies. There is high-quality evidence that suggests the use of exercise for people with knee OA can provide a reduction in pain, changes in quality of life, and have modest improvements in physical function. There is promising evidence to support that yoga for those with knee OA may improve pain intensity, function, and stiffness. The aim of this study is to establish the feasibility of a pain informed movement program, in addition to education for improving pain modulation. The data collected will be used to inform a pilot and feasibility randomized controlled trial (RCT) prior to a multi site RCT to assess the program's effectiveness with the primary outcome of change in pain severity mediated by change in descending modulation.

Eligible Conditions
  • Osteoarthritis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Acceptability of Content
Acceptability of Duration
Acceptability of Frequency
+7 more
Secondary outcome measures
Change in Brain-derived neurotrophic factor
Change in Chronic pain self-efficacy
Change in Function
+6 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Pain Informed MovementExperimental Treatment1 Intervention
This will be an 8-week in-person group exercise program held twice weekly, in which participants will receive pain Informed movement (60 minutes), with instructions provided for a third home session. Home sessions will be facilitated by exercise handout sheets. Pain education will be delivered through weekly access to videos. The pain informed movement component has been developed by a team member and will be delivered by an experienced yoga teacher.

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Who is running the clinical trial?

McMaster UniversityLead Sponsor
877 Previous Clinical Trials
2,596,046 Total Patients Enrolled
19 Trials studying Osteoarthritis
901,116 Patients Enrolled for Osteoarthritis
The Arthritis Society, CanadaOTHER
23 Previous Clinical Trials
4,880 Total Patients Enrolled
6 Trials studying Osteoarthritis
720 Patients Enrolled for Osteoarthritis
Lisa Carlesso, PhDPrincipal InvestigatorMcMaster University
3 Previous Clinical Trials
194 Total Patients Enrolled
2 Trials studying Osteoarthritis
134 Patients Enrolled for Osteoarthritis

Frequently Asked Questions

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~5 spots leftby Mar 2025