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Experimental Dentifrice 1 for Oral Hygiene

N/A
Waitlist Available
Research Sponsored by GlaxoSmithKline
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Provision of a signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study before any assessment is performed.
Participant who is willing and able to comply with scheduled visits, product usage requirements, study procedures and lifestyle restrictions.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, week 4 and week 8
Awards & highlights

Study Summary

This trial is testing how well two new experimental toothpastes work at reducing tooth sensitivity, compared to a regular fluoride toothpaste.

Eligible Conditions
  • Oral Hygiene

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, week 4 and week 8
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, week 4 and week 8 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from Baseline in Mean Total Macpherson Modification of the Lobene Stain Index (MLSI) Score at Week 8
Secondary outcome measures
Change from Baseline in Mean MLSI (Area) and MLSI (Intensity) at Weeks 4 and 8
Change from Baseline in Mean Total MLSI Score at Week 4
Change from Baseline in Mean Total MLSI Score at Weeks 4 and 8
+2 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Experimental Dentifrice 2Experimental Treatment1 Intervention
Randomized participants will brush their teeth with the experimental dentifrice (covering the entire length of the toothbrush), twice daily (morning and evening) for 2 minutes for 8 weeks.
Group II: Experimental Dentifrice 1Experimental Treatment1 Intervention
Randomized participants will brush their teeth with the experimental dentifrice (covering the entire length of the toothbrush), twice daily (morning and evening) for 2 minutes for 8 weeks.
Group III: Reference DentifriceActive Control1 Intervention
Randomized participants will brush their teeth with the Reference dentifrice (covering the entire length of the toothbrush), twice daily (morning and evening) for 2 minutes for 8 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Experimental Dentifrice 1
2022
N/A
~290
Experimental Dentifrice 2
2022
N/A
~290

Find a Location

Who is running the clinical trial?

GlaxoSmithKlineLead Sponsor
4,741 Previous Clinical Trials
8,062,583 Total Patients Enrolled
7 Trials studying Oral Hygiene
1,138 Patients Enrolled for Oral Hygiene
HALEONLead Sponsor
24 Previous Clinical Trials
3,230 Total Patients Enrolled
1 Trials studying Oral Hygiene
160 Patients Enrolled for Oral Hygiene

Frequently Asked Questions

~112 spots leftby Mar 2025