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tDCS for Opioid Addiction
Study Summary
This trial will use transcranial direct current stimulation (tDCS) on the dorsolateral prefrontal cortex (DLPFC) to study the cognitive control network (CCN) in people with opioid dependence. It will assess behavioral and brain responses using functional magnetic resonance imaging (FMRI) and electroencephalographic (EEG).
- Opioid Addiction
- Craving
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have a medical condition, such as seizures, that makes it unsafe for you to receive tDCS treatment.You are currently dependent on opioids.You have any sores or injuries on your scalp where the tDCS electrode will be placed.You have poor eyesight that can't be improved with glasses or contacts.You do not have a diagnosis of bipolar disorder, schizophrenia, schizo-affective disorder, schizophreniform disorder, or paranoid disorder according to the DSM-V guidelines.You started taking buprenorphine or methadone less than a month ago.You must be between 21 and 50 years old.You have a history of neurological conditions like epilepsy, stroke, or severe brain injury with loss of consciousness for more than 10 minutes.You are currently experiencing suicidal thoughts or behaviors.You plan to stop taking buprenorphine within the next 3 months.
- Group 1: sham tDCS
- Group 2: tDCS
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Who fulfills the criteria for joining this research project?
"This trial is seeking 160 participants with a craving disorder, who must be between 21 and 50 years old."
Is enrollment in this research study still open?
"According to clinicaltrials.gov, this research study is still enrolling participants. It was initiated on May 1st 2019 and the most up-to-date information about it was edited on November 29th 2021."
Does the protocol for this clinical trial permit persons of forty years and older to take part?
"This investigation is looking to include individuals aged between 21 and 50 years old."
How many participants are there in this clinical research project?
"Affirmative, the information found on clinicaltrials.gov verifies that this study is actively recruiting volunteers. Initially posted in May of 2019 and last updated in November 2021, 160 people are sought after to enroll at a single centre."
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