tDCS for Opioid Addiction

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Opioid Addiction+1 MoretDCS - Device
Eligibility
21 - 50
All Sexes
What conditions do you have?
Select

Study Summary

This trial will use transcranial direct current stimulation (tDCS) on the dorsolateral prefrontal cortex (DLPFC) to study the cognitive control network (CCN) in people with opioid dependence. It will assess behavioral and brain responses using functional magnetic resonance imaging (FMRI) and electroencephalographic (EEG).

Eligible Conditions
  • Opioid Addiction
  • Craving

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

5 Primary · 0 Secondary · Reporting Duration: 3 month

2 week
change in EEG oscillatory targets
change in the cognitive control network
change in the saliency network
changes in opioid craving
3 month
lower rates of opioid relapse

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

tDCS
1 of 2
sham tDCS
1 of 2

Active Control

Non-Treatment Group

160 Total Participants · 2 Treatment Groups

Primary Treatment: tDCS · Has Placebo Group · N/A

tDCS
Device
ActiveComparator Group · 1 Intervention: tDCS · Intervention Types: Device
sham tDCS
Device
ShamComparator Group · 1 Intervention: sham tDCS · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 month

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,248 Previous Clinical Trials
2,028,927 Total Patients Enrolled
5 Trials studying Opioid Addiction
1,065 Patients Enrolled for Opioid Addiction
Butler HospitalLead Sponsor
123 Previous Clinical Trials
16,438 Total Patients Enrolled
1 Trials studying Opioid Addiction
21 Patients Enrolled for Opioid Addiction
Michael D Stein, M.D.Principal InvestigatorBoston University
1 Previous Clinical Trials
147 Total Patients Enrolled
Ana M Abrantes, Ph.D.Principal InvestigatorButler Hospital
3 Previous Clinical Trials
197 Total Patients Enrolled

Eligibility Criteria

Age 21 - 50 · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have been prescribed buprenorphine or methadone for 30 days or less.