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Endodontic Regeneration for Tooth Pulp Necrosis

N/A
Waitlist Available
Led By Tatiana M Botero, DDS, MS
Research Sponsored by University of Michigan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Tooth is restorable and periodontally stable.
Cooperative.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 24 months after the induction of blood clot
Awards & highlights

Study Summary

This trial compares two methods of root canal treatment to see if they are equally effective in disinfecting the root canal and inducing blood clot formation.

Eligible Conditions
  • Tooth Pulp Necrosis
  • Dental Developmental Disorder

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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Your tooth can be fixed and is not loose.
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You are willing to work collaboratively and follow the study guidelines.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 and 24 months after the induction of blood clot
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 and 24 months after the induction of blood clot for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Absence of infection and inflammation.
Secondary outcome measures
Changes in root length and canal wall width

Trial Design

2Treatment groups
Experimental Treatment
Group I: Immediate InductionExperimental Treatment1 Intervention
Blood clot is induced after disinfection of the canal during the same visit. Endodontic regeneration is performed.
Group II: Delayed inductionExperimental Treatment1 Intervention
The root canal is disinfected and calcium hydroxide is placed in the canal. Blood clot is induced in the canal 4 weeks later. Endodontic Regeneration is performed.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Endodontic Regeneration
2012
N/A
~50

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor
1,782 Previous Clinical Trials
6,364,612 Total Patients Enrolled
Tatiana M Botero, DDS, MSPrincipal InvestigatorUniversity of Michigan

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who qualifies to participate in this research study?

"This research programme is seeking 45 participants who are between 6 and 25 years old and have a case of pulp mummification. In order to qualify, the tooth must be restorable and periodontally sound as well as the patient needing to meet general health criteria (ASA Physical Status 1 or 2) with no contraindications for treatment."

Answered by AI

Are individuals beyond the age of 30 eligible for participation in this clinical trial?

"Patients of any age between 6 and 25 are eligible to join this medical trial; 21 trials cater specifically for minors, while 66 serve people over the age of 65."

Answered by AI

Does this research study have open slots for participants?

"According to the clinicaltrials.gov platform, this research is no longer recruiting participants. Initially posted on October 1st 2012 and last updated on March 2nd 2022, it has since been concluded; however, there are 87 other trials currently searching for patients at this moment in time."

Answered by AI
Recent research and studies
~4 spots leftby Mar 2025