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Intervention for Kidney Failure

N/A
Waitlist Available
Led By Gerald Koenig, MD
Research Sponsored by Henry Ford Health System
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

Study Summary

Remote ischemic preconditioning is a process of serial blood pressure cuff inflations and deflations that are performed prior to a procedure and have been shown in various other areas (coronary bypass surgery, vascular surgery, ST elevation myocardial infarctions) to decrease the rates of adverse events related to ischemic burden and renal injury. This procedure has not yet been studied in the population presenting with an acute coronary syndrome (ACS), even though ACS patients represent the majority of patients seen in the catheterization lab. The purpose of this study is to evaluate the efficacy of this simple and safe procedure in this particular population.

Eligible Conditions
  • Kidney Failure
  • Acute Coronary Syndrome
  • Myocardial Ischemia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Ischemic Burden
Secondary outcome measures
Clinical Outcomes
Renal Injury

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: InterventionExperimental Treatment1 Intervention
This group will undergo remote ischemic preconditioning with serial inflations of the blood pressure cuff to 200 mmHg followed by deflation for reperfusion for a period of 5 minutes each for a total of 4 cycles.
Group II: ControlPlacebo Group1 Intervention
This group will undergo serial inflations of the blood pressure cuff to 40 mmHg followed by deflation for a period of 5 minutes each for a total of 4 cycles.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Remote Ischemic Preconditioning
2019
Completed Phase 4
~1420

Find a Location

Who is running the clinical trial?

Henry Ford Health SystemLead Sponsor
298 Previous Clinical Trials
2,098,747 Total Patients Enrolled
Gerald Koenig, MDPrincipal InvestigatorHenry Ford Health System

Frequently Asked Questions

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~0 spots leftby Mar 2025