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Noninvasive Brain Stimulation
Transcranial Direct Current Stimulation for Dementia
N/A
Recruiting
Led By Christian LoBue, PhD
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age 50 and older
Active diagnosis of MCI or dementia
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, immediately following last treatment session, and 2-months post treatment
Awards & highlights
Study Summary
This trial is testing whether a non-invasive brain stimulation technique can improve verbal episodic memory in patients with mild cognitive impairment or dementia.
Who is the study for?
This trial is for individuals aged 50 or older with a diagnosis of mild cognitive impairment (MCI) or dementia, who are fluent in English. It's not suitable for those with substance use disorders, metal fragments in the head, or taking certain medications that could interfere with the treatment.Check my eligibility
What is being tested?
The study tests high-definition transcranial direct current stimulation (HD-tDCS) to improve verbal memory in MCI/dementia patients. Participants will be randomly assigned to receive either low-intensity (1 mA), higher intensity (2 mA) active HD-tDCS, or a sham treatment over ten sessions.See study design
What are the potential side effects?
Potential side effects of HD-tDCS may include discomfort at the electrode site, itching, tingling during the session, headache, fatigue and nausea. However, these are usually mild and temporary.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 50 years old or older.
Select...
I have been diagnosed with mild cognitive impairment or dementia.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline, immediately following last treatment session, and 2-months post treatment
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, immediately following last treatment session, and 2-months post treatment
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in Score on the Rey Auditory Verbal Learning Test (RAVLT)
Trial Design
3Treatment groups
Experimental Treatment
Placebo Group
Group I: Active stimulation at 2mAExperimental Treatment1 Intervention
Participants will receive 2 mA active HD-tDCS for 20 minutes.
Group II: Active stimulation at 1mAExperimental Treatment1 Intervention
Participants will receive 1 mA active HD-tDCS for 20 minutes.
Group III: Sham groupPlacebo Group1 Intervention
Participants will receive sham HD-tDCS for 20 minutes, meaning no stimulation.
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Who is running the clinical trial?
University of Texas Southwestern Medical CenterLead Sponsor
1,043 Previous Clinical Trials
1,053,050 Total Patients Enrolled
Christian LoBue, PhDPrincipal InvestigatorUT Southwestern Medical Center
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have been diagnosed with mild cognitive impairment or dementia.I am 50 years old or older.I am not taking any medication that could affect the study treatment.I have been diagnosed with mild cognitive impairment or dementia.
Research Study Groups:
This trial has the following groups:- Group 1: Active stimulation at 1mA
- Group 2: Active stimulation at 2mA
- Group 3: Sham group
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is there currently an open call for participants in this study?
"The information hosted on clinicaltrials.gov conveys that at this time, no further candidates are being sought out for inclusion in the trial which was initially published 8/8/2022 and last edited 8/22/2022. Nevertheless, there exist 1,161 other trials actively seeking patient involvement right now."
Answered by AI
Who else is applying?
What site did they apply to?
UT Southwestern Medical Center
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0
What questions have other patients asked about this trial?
How long does screening take?
PatientReceived 1 prior treatment
Why did patients apply to this trial?
One 1 drug has been prescribed.
PatientReceived 2+ prior treatments
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