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Behavioral Intervention

Patient Education Program for Chronic Kidney Disease (MAGICIAN Trial)

N/A
Waitlist Available
Led By Rebecca J. Ellis, PhD
Research Sponsored by Indiana University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Self-reported ability to open a pill cap
Able to self-administer RAAS inhibiting medications
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

MAGICIAN Trial Summary

This trial compares a new patient education system against a control group in kidney disease patients taking medications to regulate blood pressure.

Who is the study for?
This trial is for adults over 18 with chronic kidney disease who are prescribed RAAS inhibiting medication but have a less than perfect track record of taking it. They must be able to manage their own medications, speak English, and not suffer from severe cognitive impairments or life-shortening conditions like metastatic cancer.Check my eligibility
What is being tested?
The MAGICIAN study compares two methods: SystemCHANGE™, which aims to improve patients' habits and routines around taking their medication, versus standard patient education (attention control). Participants will be randomly assigned to one of these groups.See study design
What are the potential side effects?
Since the interventions involve behavioral strategies rather than drugs, traditional side effects aren't expected. However, participants may experience stress or frustration if they struggle with changing habits or adhering to the program's requirements.

MAGICIAN Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can open a pill cap by myself.
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I can take my RAAS inhibitor medication by myself.
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I am older than 18 years.
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I am taking medication daily to manage my blood pressure or heart condition.
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My kidney function is reduced but not at its worst stage.
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I do not have any other life-shortening conditions.

MAGICIAN Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Personal Systems Behavior
Percentage of daily doses of medication taken as prescribed (Medication Adherence)
Secondary outcome measures
Outcome Expectancy and Credibility
The investigator-designed 10-item Acceptability Questionnaire assesses nurse-intervention interaction and mobility technology acceptability.

MAGICIAN Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: SystemCHANGE (TM)Experimental Treatment1 Intervention
SystemCHANGE™ focuses on using patients' already established and reliable systems to support medication-taking, rather than focusing on personal effort and "remembering."When applied to medication adherence, the goal is to reduce medication-taking variability and move towards consistently taking medication with a 6-hour window of time (for daily medications like RAAS) and avoid missing medications. SystemCHANGE™ improvement cycles rely on efficient use of performance feedback in order to make decisions about whether system solutions work or if there is a need to select other solutions.
Group II: Attention ControlActive Control1 Intervention
Participants in the attention control will receive educational materials about chronic kidney disease (CKD). The content will be focused on diet, exercise, and living with CKD.

Find a Location

Who is running the clinical trial?

National Institute of Nursing Research (NINR)NIH
574 Previous Clinical Trials
10,354,144 Total Patients Enrolled
Indiana UniversityLead Sponsor
973 Previous Clinical Trials
982,700 Total Patients Enrolled
Rebecca J. Ellis, PhDPrincipal InvestigatorIndiana University School of Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who meets the criteria to participate in this research initiative?

"Eligibility for this medical trial demands that participants have a diagnosis of chronic kidney disease and are between 18 to 99 years old. In total, around 120 patients will be chosen."

Answered by AI

Are participants above the age of twenty eligible to join this clinical investigation?

"The protocol for this study necessitates that all participants must be 18 to 99 years old. Additionally, there are 43 trials available for minors and 458 studies open to those aged 65 or above."

Answered by AI

Is recruitment for this trial still ongoing?

"Clinicaltrials.gov reports that this research has stopped recruiting participants and was last edited on June 13th 2022 from its initial posting date of December 15th 2021. Despite these facts, there are still 497 other trials currently seeking patients' involvement."

Answered by AI
Recent research and studies
~46 spots leftby Mar 2025