Ingestion of protein for Kidney Diseases
This study is evaluating whether a new method of measuring kidney function may be useful for predicting kidney disease.
See full descriptionAbout the trial for Kidney Diseases
Treatment Groups
This trial involves 2 different treatments. Ingestion Of Protein is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Ingestion of protein will improve 1 primary outcome in patients with Kidney Diseases. Measurement will happen over the course of Single full-day clinic visit: Repeated glomerular filtration rate measurements are to be performed over the course of the day at a single study visit for each participant..
Who is running the study
Principal InvestigatorPatient Q & A Section
Is ingestion of protein safe for people?
Protein ingestion is safe using a strict adherence to diet and exercise guidelines even in high protein calorie diets. Clinicians should not restrict protein unless there is specific data that protein is contraindicated. Protein in diet should not be compromised to avoid an increase in the protein intake.
How many people get kidney diseases a year in the United States?
About 9.2 million people in the US a year have at least one kidney disease and 2.6 million people (30,000 per hour) die with complications from kidney diseases.
Can kidney diseases be cured?
There is evidence that kidney-related diseases can be reversible, but no doubt irreversible. In patients with acute kidney disease and chronic kidney disease, they can be prevented by a careful management, and by the treatment of the underlying disease, as indicated by a multidisciplinary approach.
What is kidney diseases?
The most commonly reported problem among those surveyed was the kidney problem, and it's common in various age groups and in both genders. The cause of the kidney disease is most commonly glomerulonephritis which is found in the children and adolescents. All the problems that arose from the kidney disease had a profound effect on the patients' quality of life.
What causes kidney diseases?
As the number of people with kidney disease increases by about 3% every year, this will soon form the greatest burden of chronic illnesses. The most common condition causing chronic kidney disease is hypertension. Prevention is feasible from a variety of sources. A key feature is that interventions to improve outcomes from diabetes or hypertension are required as well as interventions for blood pressure and proteinuria. It is necessary to implement integrated approaches to tackle these conditions.
What are the signs of kidney diseases?
Urine testing for protein, nitrite, ketones, calcium, phosphate and hematuria, can be done in children, when they show any symptoms of kidney diseases such as anemia, pyuria and hematuria. But these tests alone are not sufficient. Findings from a recent study of blood and urine protein analysis should also be regarded as a warning of kidney disease.
What are common treatments for kidney diseases?
Although many treatments are effective for kidney diseases, we need additional strategies to control these diseases, and we need to evaluate which type of drugs is most appropriate for particular kidney diseases, because there may be an urgent need for preventive therapy of these diseases. Power makes it easy to find dialysis and living kidney donation clinical trials.
What is ingestion of protein?
Protein intake should be increased because it affects renal function, and proteinuria, urinary excretion of protein, alters the structure of the glomeruli, increases their basement membrane and, consequently, the glomerular filtration capacity. Results from a recent clinical trial reveals that protein intake increases, which allows the urinary excretion of protein to increase, to cause the formation of proteinuria. Because proteinuria affects hematuria, protein intake increases urinary protein excretion. Hence, protein intake should be increased to prevent or prevent the formation of hematuria.
What are the latest developments in ingestion of protein for therapeutic use?
Protein ingestion is an alternative and well-tolerated route of administration for the treatment of moderate to severe protein-energy malnutrition. Protein therapy is indicated in patients with protein to energy ratio [protein : fat] less than 0.6 and a body weight decrease over 4 weeks. Because of its potency and safety, protein therapy may have a major role for patients with protein to energy ratio lower than 0.4 to avoid malnutrition. Prokinetic peptides have the capacity to deliver proteins into target cells, overcoming the digestive or absorptive barrier function of the stomach or intestines.
How serious can kidney diseases be?
Kidney diseases occur more frequently than previously thought and may be just as important as heart disease as a cause of death. Kidney disease severity is significantly related to both CKD etiology (primary versus secondary) and stage of CKD and CKD-associated risk factors. Kidney disease treatment should extend well beyond just controlling blood pressure and cholesterol levels.
What is the average age someone gets kidney diseases?
About 30 million people in the world have chronic kidney disease (CKD stages 3–4). By the end of the year 2016, the World Health Organization projected that 562 000 people could die from CKD and 15 million people could be living with CKD on a constant basis. The global average mortality for CKD patients is estimated at 25 years old.
What are the common side effects of ingestion of protein?
Protein can cause vomiting, nausea, muscle cramps, weakness, itchiness, diarrhea and others. Itchiness and other muscle cramps can become more pronounced in persons taking certain medicines such as ACE inhibitors, Beta blockers, calcium channel blockers and diuretics. There is an increased risk of dehydration with proteins consumed prior to exercise in warm climates. There is also an increased risk of dehydration and thirst with proteins consumed in hot weather.