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Laser

Thulium Fibre Laser for Kidney Stones

N/A
Waitlist Available
Led By Mantu Gupta
Research Sponsored by Icahn School of Medicine at Mount Sinai
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients undergoing unilateral ureteroscopic laser lithotripsy for the treatment of non-obstructing renal stones
Total stone burden between 5 and 20 mm
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 1 hour postoperatively, and 10 days postoperatively
Awards & highlights

Study Summary

This trial is testing two different types of lasers to see which is better at treating kidney stones in patients. Urine samples are collected before and after the procedure to measure levels of kidney injury biomarkers.

Eligible Conditions
  • Kidney Stones

Eligibility Criteria

Inclusion Criteria

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Patients must be aged greater than or equal to 18 years.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 1 hour postoperatively, and 10 days postoperatively
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 hour postoperatively, and 10 days postoperatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Kidney Injury Molecule-1 (KIM-1)
Change in Neutrophil Gelatinase-associated Lipocalin (NGAL)
Change in β2-microglobulin (β2M)
Secondary outcome measures
Operative Time

Trial Design

2Treatment groups
Experimental Treatment
Group I: Thulium Fibre Laser (TFL)Experimental Treatment1 Intervention
Patients who are randomized to undergo ureteroscopic laser lithotripsy with the Thulium fibre laser (TFL)
Group II: Holmium:Yttrium-Aluminum-Garnet (Ho:YAG)Experimental Treatment1 Intervention
Patients who are randomized to undergo ureteroscopic laser lithotripsy with the Holmium:Yttrium-Aluminum-Garnet (Ho:YAG) laser
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Thulium Fibre Laser
2022
N/A
~190
Holmium:Yttrium-Aluminum-Garnet
2022
N/A
~190

Find a Location

Who is running the clinical trial?

Icahn School of Medicine at Mount SinaiLead Sponsor
852 Previous Clinical Trials
535,824 Total Patients Enrolled
Mantu GuptaPrincipal InvestigatorDepartment of Urology, Icahn School of Medicine at Mount Sinai

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there room for more participants in this experiment?

"The current status of this trial, as indicated by clinicaltrials.gov, is that it is recruiting participants. The trial was originally posted on October 22nd, 2021 and was last edited on April 22nd, 2022."

Answered by AI

Are there any limitations as to how many people can enroll in this experiment?

"That is correct, the listing on clinicaltrials.gov says that this research trial is open for recruitment. The trial was first advertised on October 22nd, 2021 and was last updated on April 22nd, 2022. They are looking for 108 individuals total from 1 location."

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
New York
How old are they?
65+
What site did they apply to?
Mount Sinai West
What portion of applicants met pre-screening criteria?
Met criteria
~32 spots leftby Mar 2025