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Exercise Snacks for Sarcopenia

N/A
Recruiting
Led By Daniel R Moore, PhD
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy older adults aged 60-80 years
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 hours
Awards & highlights

Study Summary

This trial tests how reduced physical activity and "exercise snacks" affect muscle health.

Who is the study for?
This trial is for healthy older adults aged 60-80 with a BMI of 18.5-29.9, who can follow the study's rules like not walking more than 1,500 steps/day during part of the study. People with recent cancer, chronic illnesses like heart disease or diabetes, those using walkers or tobacco, and those on certain medications like anticoagulants can't join.Check my eligibility
What is being tested?
The trial tests if doing 'exercise snacks' (15 chair stands with calf raises every half hour) can help maintain muscle health when older adults have been less active (<1500 steps/day) for three days.See study design
What are the potential side effects?
Since this intervention involves light physical activity, potential side effects may include muscle soreness or fatigue. However, as it's designed for older individuals without major health issues, serious side effects are unlikely.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 60 and 80 years old and in good health.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Myofibrillar protein synthesis rates
Secondary outcome measures
Amino acid oxidation and net protein balance
Postprandial glucose area under the curve (AUC) to mixed macronutrient breakfast
Postprandial insulin area under the curve (AUC) to mixed macronutrient breakfast
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Step-ReductionExperimental Treatment2 Interventions
Participants will undergo three days of reduced physical activity (<1,500 steps/day) prior to a metabolic trial to establish their anabolic response to a protein-carbohydrate meal.
Group II: Habitual ActivityExperimental Treatment1 Intervention
Following three days of habitual activity, a metabolic trial will be completed wherein participants (10M/10F) will be assessed for their anabolic response to a protein-carbohydrate meal.

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
687 Previous Clinical Trials
1,018,350 Total Patients Enrolled
Daniel R Moore, PhDPrincipal InvestigatorUniversity of Toronto
5 Previous Clinical Trials
54 Total Patients Enrolled
Hugo JW Fung, PhDStudy DirectorUniversity of Toronto

Media Library

Metabolic Trial Clinical Trial Eligibility Overview. Trial Name: NCT05810272 — N/A
Neuromuscular Symptoms Research Study Groups: Habitual Activity, Step-Reduction
Neuromuscular Symptoms Clinical Trial 2023: Metabolic Trial Highlights & Side Effects. Trial Name: NCT05810272 — N/A
Metabolic Trial 2023 Treatment Timeline for Medical Study. Trial Name: NCT05810272 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Could I be qualified to enroll in this trial?

"To be eligible for this clinical trial, candidates must meet the criteria of physical inactivity and an age range between 60 to 80 years old. This particular study is recruiting roughly 20 participants."

Answered by AI

Does this clinical trial cater to individuals aged sixty and above?

"The requirements for enrolment in this trial are that patients must be between sixty and eighty years old. On the other hand, there exist 84 trials for individuals under eighteen years of age and 638 studies available to those above 65."

Answered by AI

Are participants being accepted for this trial currently?

"According to recent updates on clinicaltrials.gov, this research project is recruiting participants at present. It was first announced on April 1st 2023 and underwent a revision as recently as March 30th of the same year."

Answered by AI

How many participants are authorized to take part in this research effort?

"Affirmative. According to the resources hosted on clinicaltrials.gov, this medical experiment was posted on April 1st 2023 and is currently enrolling participants. As of March 30th 2023, there are only 20 spots open at a single test site remaining for recruitment."

Answered by AI
~10 spots leftby Mar 2025