REDUCE-BP Intervention for Hypertension

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Advocate Health Care, Chicago, IL
Hypertension+1 More
REDUCE-BP Intervention - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a set of tools can improve blood pressure control in primary care.

See full description

Eligible Conditions

  • Hypertension
  • Blood Pressures

Treatment Effectiveness

Study Objectives

This trial is evaluating whether REDUCE-BP Intervention will improve 1 primary outcome and 4 secondary outcomes in patients with Hypertension. Measurement will happen over the course of 12 months.

12 months
Change in systolic blood pressure
Clinical encounters
Percentage of patients with guideline-concordant medications
Percentage of patients with intensification of medication
Percentage of patients with well-controlled blood pressure

Trial Safety

Trial Design

2 Treatment Groups

Control Arm
1 of 2
Intervention Arm
1 of 2
Active Control
Experimental Treatment

This trial requires 2000 total participants across 2 different treatment groups

This trial involves 2 different treatments. REDUCE-BP Intervention is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Intervention Arm
Behavioral
Providers within the clinics randomized to the intervention arm will receive a variety of EHR-based tools for eligible patients with uncontrolled hypertension.
Control ArmProviders within the clinics randomized to usual care will receive no EHR tools, except those currently available in clinical practice.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 12 months for reporting.

Who is running the study

Principal Investigator
N. K. C.
Prof. Niteesh K. Choudhry,, MD PhD
Brigham and Women's Hospital

Closest Location

Advocate Health Care - Chicago, IL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
type The patient has been diagnosed with hypertension at least twice within the last 24 months. show original
There is a recent trend of blood pressure measurements ≥140 or ≥90 when taken as outpatient/ambulatory care (excluding urgent care), as measured over the past 12 months show original
87% of patients had 1 visit with PCP in past 2 years ( rolling 24 months) This statistic measures how often, on average, a patient sees their PCP in the past 2 years. show original
The current age range is 18-85 years. show original

Patient Q&A Section

What are common treatments for hypertension?

"Some treatments for hypertension are not used in a satisfactory proportion of the United States population. Other treatments are more commonly used. The use of blood pressure-lowering drugs varies widely by race and ethnicity, with the lowest use among African Americans and Hispanics." - Anonymous Online Contributor

Unverified Answer

What causes hypertension?

"Diabetes and high blood pressure cause damage to the wall of arterioles, and the body responds by building larger arterioles or arteriole walls, or both. Both [type 2 diabetes](https://www.withpower.com/clinical-trials/type-2-diabetes) and high blood pressure increase the risk of many types of cardiovascular disease." - Anonymous Online Contributor

Unverified Answer

What is hypertension?

"Many essential hypertensive patients do not know about this condition and its role in their cardiovascular, neurological and other manifestations. Most of them think that hypertension is just a 'natural' part of the aging population, but hypertension is actually one of the main causes of death worldwide, mainly due to the cardiovascular and CVD complications. There are two major ways of defining this disease: one approach is to say that hypertension is a blood pressure ≥150<180/110mmHg over 3–5 years, while the global arterial stiffness index, with noninvasive measurement of arterial elasticity, adds a complementary approach to this definition. The main risk factors for hypertension and its complications are age, race, genetics, diet, exercise, and obesity." - Anonymous Online Contributor

Unverified Answer

How many people get hypertension a year in the United States?

"In the age group 55-89 years, the United States has the highest annual prevalence of hypertension in Caucasians in the world. A high prevalence of hypertension was observed also in South Asian immigrants who arrived during the 1980s, the year of the peak immigration to the United States." - Anonymous Online Contributor

Unverified Answer

Can hypertension be cured?

"A significant proportion of the hypertensives do not achieve an optimum level of BP, and many of those who do achieve an optimum level have high BP levels. Therefore, further studies should be conducted to confirm whether regular use of antihypertensive drugs can ensure optimal BP control in the entire population and minimize the burden of uncontrolled hypertension." - Anonymous Online Contributor

Unverified Answer

What are the signs of hypertension?

"Symptoms of hypertension include headache, flushing of eyes or face, and feeling lightheaded or dizzy when standing up. Blood pressure is a primary preventive measure; screening blood pressure in children is especially important for young children." - Anonymous Online Contributor

Unverified Answer

Does hypertension run in families?

"Despite the growing body of evidence demonstrating the important significance of hypertension in the aetiology of coronary heart disease and stroke, these data emphasise that hypertension does not run in families. These data support a model of development whereby genetic factors determine a predisposition to hypertension in a narrow subgroup of individuals, while secondary factors act as triggers in the development of hypertension." - Anonymous Online Contributor

Unverified Answer

How serious can hypertension be?

"People with pre-hypertensive blood pressure respond to change to normal blood pressure if they take part in an integrated program of behavior modifications, a medication regimen, referral to a hypertension specialist, and frequent clinic visits. However, even among medically managed hypertensive persons, a relatively low proportion achieve target blood pressure levels." - Anonymous Online Contributor

Unverified Answer

What is the latest research for hypertension?

"This information is not intended to be an exhaustive list of all the best treatment options. This article will present the available information on treatment of hypertension." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for hypertension?

"A clinical trial with an intervention like the one used in this study was worthwhile if the intervention would have a positive impact on clinical endpoints of the trial. Patients with low disease burden, or with co-morbidities or with contraindications to the intervention should not participate in a clinical trial as the risk of a statistical error with too few subjects would be unacceptable." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets hypertension?

"The average age that someone got hypertension is in the late 30s to early 40-s. (Age 40 yr = 17.2; Age 45 yr = 16.3 y; Age 49 yr = 17." - Anonymous Online Contributor

Unverified Answer

Has reduce-bp intervention proven to be more effective than a placebo?

"Recent findings indicated the usefulness of a reduction-bp intervention for improving blood pressure control, thereby contributing to the reduction of the mortality rate in the elderly." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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