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Computerized Decision Support for Pulmonary Hypertension (CTEPH-DETECT Trial)

N/A
Waitlist Available
Led By Gregory Piazza, MD, MS
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Persistent or new symptoms/signs suggestive of pulmonary hypertension [syncope, malaise and fatigue, dyspnea, exercise intolerance, hemoptysis, chest pain, dizziness/vertigo, gait abnormality, cardiomegaly, ascites, and peripheral edema] OR recent pulmonary testing (pulmonary function tests [PFTs], chest X-ray, or chest CT) suggesting unexplained respiratory symptoms at least 6 months from the diagnosis of PE
At least 18 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months
Awards & highlights

CTEPH-DETECT Trial Summary

This trial will test whether or not an electronic health record alert will increase echocardiographic screening for CTEPH and the diagnosis of CTEPH in patients with prior pulmonary embolism and symptoms/signs suggestive of pulmonary hypertension or recent pulmonary testing suggesting unexplained respiratory symptoms.

Who is the study for?
This trial is for adults who've had a pulmonary embolism, are experiencing symptoms like fatigue or chest pain, or have unexplained respiratory issues on tests. They haven't had an echocardiogram in the last 6 months and are seen at specific clinics.Check my eligibility
What is being tested?
The study is testing if a computer alert for doctors increases screening and diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) in patients with past pulmonary embolisms showing certain symptoms.See study design
What are the potential side effects?
Since this trial involves a computerized decision support system rather than medication, there are no direct side effects from interventions being tested.

CTEPH-DETECT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have symptoms or test results suggesting high blood pressure in the lungs.
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I am 18 years old or older.

CTEPH-DETECT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Frequency of echocardiographic screening for CTEPH in patients with prior PE and symptoms/signs suggestive of pulmonary hypertension or recent pulmonary testing suggesting unexplained respiratory symptoms at 3 months following randomization.
Secondary outcome measures
Frequency of CTEPH diagnosis at three months.

CTEPH-DETECT Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: AlertExperimental Treatment1 Intervention
On-screen computerized decision support alert during the outpatient clinical encounter that notifies the provider that the patient should be screened for CTEPH
Group II: No AlertActive Control1 Intervention
No provider notification

Find a Location

Who is running the clinical trial?

BayerIndustry Sponsor
2,229 Previous Clinical Trials
25,325,037 Total Patients Enrolled
Brigham and Women's HospitalLead Sponsor
1,599 Previous Clinical Trials
11,462,114 Total Patients Enrolled
Gregory Piazza, MD, MSPrincipal InvestigatorBWH
4 Previous Clinical Trials
10,470 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total number of volunteers taking part in this research experiment?

"Affirmative. According to the information displayed on clinicaltrials.gov, this research is actively recruiting participants since its inception on March 1st 2019 and most recent update of April 5th 2022. 400 volunteers are sought from a single site for participation in this trial."

Answered by AI

Is the trial currently recruiting participants?

"Clinicaltrials.gov confirms that this clinical trial is currently recruiting patients, having first been posted on March 1st 2019 and latest updated on April 5th 2022."

Answered by AI
~67 spots leftby Mar 2025