Treatment for Hypertension

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Duke University Medical Center, Durham, NC
Hypertension+1 More
Eligibility
18 - 65
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a sleep disorder may be associated with an increased risk of cardiovascular disease.

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Eligible Conditions

  • Hypertension
  • Insomnia

Treatment Effectiveness

Study Objectives

This trial is evaluating whether Treatment will improve 3 primary outcomes and 11 secondary outcomes in patients with Hypertension. Measurement will happen over the course of 6 week, 12 week.

6 week, 12 week
Change in nighttime sympathetic nervous system activity
6 week, 6 month
Change in arterial stiffness
Change in cardiac function
Change in cardiac structure
Month 6
Change in Office Blood Pressure
Change in awake blood pressure
Change in blood pressure during the nighttime sleep period
Change in lipid profile
Change in nighttime blood pressure dipping
Change in sleep during the nighttime sleep period
Change in sleep fragmentation during the nighttime sleep period
Change in subjective sleep quality
Change in vascular endothelial function
Changes in insomnia severity

Trial Safety

Trial Design

0 Treatment Group

This trial requires 150 total participants across 0 different treatment group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 6 week, 12 week, 6 month
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline, 6 week, 12 week, 6 month for reporting.

Closest Location

Duke University Medical Center - Durham, NC

Eligibility Criteria

This trial is for patients born any sex between 18 and 65 years old. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Systolic BP ≥ 130 mm Hg based upon two standardized BP screening assessments
A current diagnosis of insomnia disorder as defined in the International Classification of Sleep Disorders (ICSD-3); or undiagnosed, but suspected, insomnia disorder that is confirmed at their screening lab visit

Patient Q&A Section

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Other questions from users

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any geographic restrictions to consider when applying for this trial?

Patients from any state can participate in this trial, so long as they are able to attend all treatment sessions.

Will my insurance cover participating in this trial?

In order to understand how insurance coverage works for this trial, you will need to contact the study coordinator.

See if you qualify for this trial
Get access to this novel treatment for Hypertension by sharing your contact details with the study coordinator.