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Adherence Intervention for High Cholesterol (ADH-Wizard Trial)

N/A
Waitlist Available
Led By JoAnn M Sperl-Hillen, MD
Research Sponsored by HealthPartners Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
A. In the 12 months prior to the index visit, most recent A1C ≥8% AND have one or more active non-insulin glycemic medications on their electronic health record (EHR) medication list AND a potential adherence issue for one or more of these medications based on the Epic Medication Adherence score (e-PDC <80%, moderate or high confidence).
B. Two consecutive encounters with BP values ≥140/90 mm Hg AND one or more BP medications on their EHR medication list AND a potential adherence issue identified (e-PDC <80%, moderate/high confidence).
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months after an index visit
Awards & highlights

ADH-Wizard Trial Summary

This trial is testing a new way to help people with diabetes, hypertension, or lipid disorders stay on their medication. The intervention uses pharmacists to provide personalized support and information to patients identified as being at risk for not taking their medication. The intervention is based on the World Health Organization's information-motivation-behavioral framework and is designed to be integrated into primary care.

Eligible Conditions
  • High Cholesterol
  • High Blood Pressure
  • Diabetes
  • Medication Nonadherence

ADH-Wizard Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

ADH-Wizard Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months after an index visit
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months after an index visit for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Blood Pressure Medication Adherence
Mean Change in A1c
Mean Change in Systolic Blood Pressure
+2 more
Secondary outcome measures
Clinic-based Medical Care Costs

ADH-Wizard Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Adherence InterventionExperimental Treatment1 Intervention
Patients in the medication adherence enhanced clinical decision support received the enhanced decision support intervention over a 6 month period. Patients were accrued over 6 months and followed for 12 months at which point they were assessed for improved medication adherence and clinical outcomes.
Group II: Usual CareActive Control1 Intervention
Patients in the usual care arm receive the basic cardiovascular related clinical decision support which is considered standard of care at the organization.

Find a Location

Who is running the clinical trial?

HealthPartners InstituteLead Sponsor
183 Previous Clinical Trials
3,710,609 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,814 Previous Clinical Trials
47,285,454 Total Patients Enrolled
JoAnn M Sperl-Hillen, MDPrincipal InvestigatorHealthPartners Institute
2 Previous Clinical Trials
6,636 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are geriatric individuals being accepted as participants in this experiment?

"According to the criteria for participation, individuals aged 18 or above and below 75 may enroll in this medical trial."

Answered by AI

Are there vacancies for participants in this investigation?

"Cited on clinicaltrials.gov, this medical trial is not presently recruiting patients after commencing the search on August 19th 2020 and concluding it in May 5th 2022. Although no longer enrolling candidates, there are still 940 other trials actively seeking participants at this time."

Answered by AI

To whom is enrolment in this trial accessible?

"This clinical trial is in search of 8357 participants aged 18 to 75 who have been diagnosed with lipidemia. To be considered eligible, patients must also possess one or more active non-insulin glycemic medications on their electronic health record (EHR) medication list and present a potential adherence issue for these drugs according to the Epic Medication Adherence score (e-PDC <80%, moderate/high confidence). Additionally, they need two consecutive BP values ≥140/90 mm Hg AND one or more BP medications on their EHR medication list along with an observed adherence problem identified through e-PDC (<80%). Furthermore,"

Answered by AI
Recent research and studies
~1183 spots leftby Mar 2025