← Back to Search

Other

General Anesthesia for Hip Fracture (REGAIN Trial)

N/A
Waitlist Available
Led By Mark D Neuman, MD, MSc
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Clinically or radiographically diagnosed intracapsular or extracapsular hip fracture
Planned surgical treatment via hemiarthroplasty, total hip arthroplasty or appropriate fixation procedure
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during initial hospitalization until day of discharge or 30 days after randomization, whichever occurs first
Awards & highlights

REGAIN Trial Summary

This trial is comparing two types of anesthesia to see if one is better for hip fracture patients.

Eligible Conditions
  • Hip Fracture

REGAIN Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

REGAIN Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during initial hospitalization until day of discharge or 30 days after randomization, whichever occurs first
This trial's timeline: 3 weeks for screening, Varies for treatment, and during initial hospitalization until day of discharge or 30 days after randomization, whichever occurs first for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Death or inability to walk 10 feet or across a room without human assistance
Secondary outcome measures
Ability to return to home
Acute postoperative pain
All-cause mortality
+8 more

REGAIN Trial Design

2Treatment groups
Active Control
Group I: General AnesthesiaActive Control1 Intervention
Approximately half of the subjects will be randomized to the arm which receives General Anesthesia.
Group II: Regional AnesthesiaActive Control1 Intervention
Approximately half of the subjects will be randomized to the arm which receives Regional Anesthesia.

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
1,992 Previous Clinical Trials
42,873,512 Total Patients Enrolled
1 Trials studying Hip Fracture
15 Patients Enrolled for Hip Fracture
Patient-Centered Outcomes Research InstituteOTHER
548 Previous Clinical Trials
29,994,739 Total Patients Enrolled
Mark D Neuman, MD, MScPrincipal InvestigatorUniversity of Pennsylvania
1 Previous Clinical Trials
517,611 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
~203 spots leftby Mar 2025