HeartGPS for Mothers of Infants With Heart Defects

Not yet recruiting at 16 trial locations
SP
JE
Overseen ByJulie E Miller
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Carelon Research
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This is a two-arm, prospective, longitudinal, randomized controlled trial (RCT) that will compare usual care to usual care plus a prenatally initiated, virtually administered psychological intervention, called HeartGPS.

Who Is on the Research Team?

NK

Nadine Kasparian, PhD, PMH-C, FAHA

Principal Investigator

Cincinatti Children's Hospital

Are You a Good Fit for This Trial?

This trial is for pregnant women or new mothers whose baby has been diagnosed with a serious heart defect (CHD) between 16 and 30 weeks of pregnancy, where the baby will need heart surgery or a procedure soon after birth. Participants must be carrying one baby, plan to continue the pregnancy and treatment, and speak English or Spanish.

Inclusion Criteria

My congenital heart disease was diagnosed between 16 and 30 weeks of pregnancy.
I am pregnant with one baby.
I am pregnant and plan to continue my pregnancy and have surgery or a procedure for my baby.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Prenatal Intervention

Participants receive the HeartGPS intervention, which includes eight virtually administered counseling sessions, tailored educational resources, and a mental health care plan

36 weeks gestation
8 virtual sessions

Postpartum Follow-up

Participants are monitored for maternal mental health and infant development outcomes

12 months postpartum
Regular assessments at 1-2 months, 4 months, and 12 months postpartum

What Are the Treatments Tested in This Trial?

Interventions

  • HeartGPS

Trial Overview

The study compares standard care alone versus standard care plus HeartGPS—a virtual psychological support program started during pregnancy—for mothers of babies with CHD. Participants are randomly assigned to either group.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: HeartGPSExperimental Treatment1 Intervention
Group II: Usual Fetal Cardiac CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Carelon Research

Lead Sponsor

Trials
76
Recruited
125,000+