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Arrhythmic independent stimulation for Executive Function

University of North Carolina at Chapel Hill, Chapel Hill, NC
Executive FunctionArrhythmic independent stimulation - Device
Eligibility
18 - 65
All Sexes
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Study Summary

This trial will test whether transcranial magnetic stimulation can improve cognitive control by delivering stimulation to the prefrontal cortex and parietal cortex.

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

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Study Objectives

2 Primary · 1 Secondary · Reporting Duration: 1 month

1 month
Average phase lag of functional connectivity between frontal and parietal cortex in theta-frequency
Number of remembered items
Strength of functional connectivity between frontal and parietal cortex in theta-frequency

Trial Safety

Phase-Based Safety

1 of 3

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Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

Theta Stimulation followed by Alpha Stimulation
1 of 2
Alpha Stimulation followed by Theta Stimulation
1 of 2

Experimental Treatment

48 Total Participants · 2 Treatment Groups

Primary Treatment: Arrhythmic independent stimulation · No Placebo Group · N/A

Theta Stimulation followed by Alpha StimulationExperimental Group · 6 Interventions: Arrhythmic independent stimulation, Theta-frequency near-zero phase lag stimulation, Theta-frequency anti-synchrony stimulation, Arrhythmic near-zero phase lag stimulation, Alpha-frequency near-zero phase lag stimulation, Alpha-frequency anti-synchrony stimulation · Intervention Types: Device, Device, Device, Device, Device, Device
Alpha Stimulation followed by Theta StimulationExperimental Group · 6 Interventions: Arrhythmic independent stimulation, Theta-frequency near-zero phase lag stimulation, Theta-frequency anti-synchrony stimulation, Arrhythmic near-zero phase lag stimulation, Alpha-frequency near-zero phase lag stimulation, Alpha-frequency anti-synchrony stimulation · Intervention Types: Device, Device, Device, Device, Device, Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 1 month

Who is running the clinical trial?

University of North Carolina, Chapel HillLead Sponsor
1,398 Previous Clinical Trials
3,748,863 Total Patients Enrolled
National Institute of Mental Health (NIMH)NIH
2,619 Previous Clinical Trials
1,983,013 Total Patients Enrolled
Flavio Frohlich, PhDPrincipal InvestigatorUniversity of North Carolina, Chapel Hill
16 Previous Clinical Trials
485 Total Patients Enrolled

Eligibility Criteria

Age 18 - 65 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You must be right-handed.
You must have normal vision and not be color blind.
References

Frequently Asked Questions

Does this research endeavor admit participants over 25 years of age?

"This particular research trial is restricted to individuals between the ages of 18 and 65. However, there are additional medical studies for those under 18 years old (4) and over 65 (6)." - Anonymous Online Contributor

Unverified Answer

Are there any open enrollment periods for this scientific experiment?

"The clinical trial is actively enrolling participants, according to the latest update on clinicaltrials.gov. This medical research was originally advertised on January 24th 2022 and has undergone a recent change as of February 18th 2022." - Anonymous Online Contributor

Unverified Answer

How many participants are currently being surveyed in this experiment?

"Confirmed. Data hosted on clinicaltrials.gov reveals that this medical trial, which was first published on January 24th 2022, is actively looking for participants. Approximately 48 patients need to be accepted at a single site." - Anonymous Online Contributor

Unverified Answer

Might I meet the criteria to join this research endeavor?

"To participate in this medical trial, individuals must possess sound executive function and be within the ages of majority to seniority. At present, 48 participants are being sought after." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

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