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CPE for Dysgeusia

N/A
Waitlist Available
Research Sponsored by Rutgers University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
PROP insensitive individuals (PROP non-tasters; homozygous recessive for tas2R38 gene)
PROP high-sensitive individuals (PROP super-tasters; homozygous dominant for tas2R38 gene)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 days after control intervention; 11 days after experimental intervention
Awards & highlights

Study Summary

This trial looks at the effects of a daily cranberry extract oral rinse on salivary protein responses and the oral microbiome in healthy adults.

Eligible Conditions
  • Dysgeusia
  • Dry Mouth

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 days after control intervention; 11 days after experimental intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 days after control intervention; 11 days after experimental intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Composition of Oral Microbiome
Levels of Salivary Proteins
Taste and Flavor Intensity Ratings

Trial Design

2Treatment groups
Experimental Treatment
Group I: PROP super-taster subjectsExperimental Treatment2 Interventions
This arm will comprise of PROP super-taster subjects. Subjects will use a cranberry-derived oral rinse twice a day for 11 days following a 3-day control-rinse period.
Group II: PROP non-taster subjectsExperimental Treatment2 Interventions
This arm will comprise of PROP non-taster subjects. Subjects will use a cranberry-derived oral rinse twice a day for 11 days following a 3-day control-rinse period.

Find a Location

Who is running the clinical trial?

Rutgers UniversityLead Sponsor
112 Previous Clinical Trials
2,803,859 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~7 spots leftby Mar 2025