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Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
PROP insensitive individuals (PROP non-tasters; homozygous recessive for tas2R38 gene)
PROP high-sensitive individuals (PROP super-tasters; homozygous dominant for tas2R38 gene)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 days after control intervention; 11 days after experimental intervention
Awards & highlights
Study Summary
This trial looks at the effects of a daily cranberry extract oral rinse on salivary protein responses and the oral microbiome in healthy adults.
Eligible Conditions
- Dysgeusia
- Dry Mouth
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 3 days after control intervention; 11 days after experimental intervention
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 days after control intervention; 11 days after experimental intervention
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Composition of Oral Microbiome
Levels of Salivary Proteins
Taste and Flavor Intensity Ratings
Trial Design
2Treatment groups
Experimental Treatment
Group I: PROP super-taster subjectsExperimental Treatment2 Interventions
This arm will comprise of PROP super-taster subjects. Subjects will use a cranberry-derived oral rinse twice a day for 11 days following a 3-day control-rinse period.
Group II: PROP non-taster subjectsExperimental Treatment2 Interventions
This arm will comprise of PROP non-taster subjects. Subjects will use a cranberry-derived oral rinse twice a day for 11 days following a 3-day control-rinse period.
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Who is running the clinical trial?
Rutgers UniversityLead Sponsor
112 Previous Clinical Trials
2,803,859 Total Patients Enrolled
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