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Be Mindful for Major Depressive Disorder

N/A
Waitlist Available
Led By John E Roberts, PhD
Research Sponsored by State University of New York at Buffalo
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
currently experiencing mild to moderate depressive symptoms (Patient Health Questionnaire 9 Current scores between 5 and 14)
meet Diagnostic and Statistical Manual of Mental Disorders (fifth edition; DSM-5) criteria for Past Major Depressive Disorder (determined by clinical interview)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at regular intervals until 3-month follow-up (approximately 4-5 months after the start of the study)
Awards & highlights

Study Summary

This trial is testing whether a 4-week online Mindfulness-Based Cognitive Therapy course (Be Mindful) can help reduce depressive symptoms in people with a history of depression.

Eligible Conditions
  • Major Depressive Disorder (MDD)
  • Depression

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You currently have mild to moderate depression, with a score of 5 to 14 on the Patient Health Questionnaire 9.
Select...
You have experienced a major depressive episode in the past (as determined by a clinical interview following DSM-5 guidelines).

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at regular intervals until 3-month follow-up (approximately 4-5 months after the start of the study)
This trial's timeline: 3 weeks for screening, Varies for treatment, and at regular intervals until 3-month follow-up (approximately 4-5 months after the start of the study) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mean Change in Depressive Symptoms from Baseline as Measured by the Patient Health Questionnaire 9 Post-Intervention
Mean Change in Depressive Symptoms from Baseline as Measured by the Patient Health Questionnaire 9 at 3-Month Follow-Up
Secondary outcome measures
Mean Change in Decentering from Baseline as Measured by the Toronto Mindfulness Scale
Mean Change in Dysfunctional Attitudes from Baseline as Measured by the Dysfunctional Attitudes Scale (Short Form 1)
Mean Change in Dysfunctional Attitudes from Baseline as Measured by the Rosenberg Self-Esteem Scale
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Waitlist ControlExperimental Treatment1 Intervention
The Waitlist Control condition will be provided with access to the 4-week online Mindfulness-Based Cognitive Therapy course "Be Mindful" approximately 4 months after randomization to group.
Group II: InterventionExperimental Treatment1 Intervention
The Intervention condition will be provided with access to the 4-week online Mindfulness-Based Cognitive Therapy course "Be Mindful" immediately after randomization to group.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Be Mindful
2021
N/A
~380

Find a Location

Who is running the clinical trial?

State University of New York at BuffaloLead Sponsor
244 Previous Clinical Trials
49,320 Total Patients Enrolled
John E Roberts, PhDPrincipal InvestigatorState University of New York at Buffalo
Meghan E Bauer, MAPrincipal InvestigatorState University of New York at Buffalo

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What objectives are researchers hoping to accomplish with this experiment?

"The primary outcome that will be assessed on a weekly basis for approximately one to two months is the mean change in depressive symptoms from baseline, evaluated by Patient Health Questionnaire 9 at 3-month follow-up. Secondary outcomes include mean changes in dysfunctional attitudes (Rosenberg Self-Esteem Scale: 0 - strongly disagree; 3 - strongly agree), self-compassion (Self Compassion Scale Short Form: 1 - almost never; 4 – almost always) and rumination (Ruminative Response Questionnaire: 1 - almost never; 4 – almost always)."

Answered by AI

Does this clinical trial accommodate participants over the age of 45?

"This research is looking for participants of legal age and below retirement who are willing to partake in the trial."

Answered by AI

Are there still vacancies available for those interested in participating in this research?

"Clinicaltrials.gov conveys that, while initially posted on March 30th 2021 and updated as recently as August 4th 2022, this trial is not currently enrolling patients. However, there are 1289 other studies actively seeking enrolment at present."

Answered by AI

Would I be a suitable candidate to partake in this clinical research?

"This medical research is enrolling 137 people, aged 18 to 65 with mental depression. Applicants must possess current mild to moderate depressive symptoms (as gauged by Patient Health Questionnaire 9 scores of 5-14), and meet DSM-5 criteria for a Past Major Depressive Disorder as determined via clinical interview."

Answered by AI
~35 spots leftby Mar 2025