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Saline Nasal Irrigation for COVID-19

N/A
Waitlist Available
Led By Kyle Kimura, MD
Research Sponsored by Vanderbilt University Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients testing positive for COVID-19 at Vanderbilt University Medical Center or VUMC-associated testing centers
Age of 18 years or greater
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 1 to day 21
Awards & highlights

Study Summary

This trial is testing whether nasal saline or nasal saline with baby shampoo irrigations can decrease viral shedding/viral load and viral transmission, secondary bacterial load, nasopharyngeal inflammation in patients infected with the novel SARS-CoV-2.

Eligible Conditions
  • COVID-19

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 1 to day 21
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 to day 21 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Nasopharynx
Change in Viral Load in the nasopharynx over the course of COVID-19 infection
Change in microbial load in the nasopharynx
Secondary outcome measures
Symptom assessment
Temperature assessment

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Saline with Baby Shampoo Nasal IrrigationExperimental Treatment1 Intervention
Nasal irrigation BID with normal saline and 1/2 teaspoon baby shampoo
Group II: Saline Nasal IrrigationExperimental Treatment1 Intervention
Nasal irrigation BID with normal saline
Group III: Control Group, No interventionActive Control1 Intervention
control group, no nasal irrigation

Find a Location

Who is running the clinical trial?

Vanderbilt University Medical CenterLead Sponsor
850 Previous Clinical Trials
669,037 Total Patients Enrolled
20 Trials studying COVID-19
42,808 Patients Enrolled for COVID-19
Kyle Kimura, MDPrincipal InvestigatorVanderbilt University Medical Center
Justin H. Turner, MD, PhDStudy DirectorVanderbilt University Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~19 spots leftby Mar 2025