Combined Aerobic Exercise and Resistance Training (AE + RT) for Mild Cognitive Impairment
Study Summary
This trial will test the feasibility of delivering exercise and cognitive interventions to older adults at risk for developing Alzheimer's Disease and Related Dementias in the home, as well as assess participants' preferences for these interventions.
- Mild Cognitive Impairment
Treatment Effectiveness
Effectiveness Progress
Study Objectives
2 Primary · 64 Secondary · Reporting Duration: Baseline, post-intervention at 4 months, and follow-up at 10 months
Trial Safety
Safety Progress
Trial Design
4 Treatment Groups
Control Exercise Training and Cognitive Intervention Training
1 of 4
Exercise Intervention Training and Control Cognitive Training
1 of 4
Exercise Intervention Training and Cognitive Intervention Training
1 of 4
Control Exercise Training and Control Cognitive Training
1 of 4
Active Control
Experimental Treatment
Non-Treatment Group
60 Total Participants · 4 Treatment Groups
Primary Treatment: Combined Aerobic Exercise and Resistance Training (AE + RT) · Has Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 60 - 90 · All Participants · 11 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- McGibbon, Chris, Pam Jarrett, Grant Handrigan, Danielle Bouchard, Carole C Tranchant, Andrew M Sexton, Linda Yetman, et al.. 2022. “Protocol for Synchronising Exercises, Remedies in Gait and Cognition at Home (synergic@home): Feasibility of a Home-based Double-blind Randomised Controlled Trial to Improve Gait and Cognition in Individuals at Risk for Dementia”. BMJ Open. BMJ. doi:10.1136/bmjopen-2021-059988.
- Chris A. McGibbon, PhD 2021. "SYNchronizing Exercises, Remedies in Gait and Cognition at Home (SYNERGIC@Home)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04997681.
Frequently Asked Questions
What are the projected results from this clinical exploration?
"This medical trial's primary goal, which will be tracked for 4 months post-intervention, is to measure patients' preference of the intervention. Secondary objectives include assessing changes in quality of life through a 36-item questionnaire (SF-36), clinical frailty by using a 9 point scale (CFS), and dietary habits via a 14 item survey (MDA-14)." - Anonymous Online Contributor
How many individuals can participate in this research project?
"Affirmative. The clinicaltrials.gov website verifies that this investigation is actively recruiting participants, which was initially posted on July 28th 2021 and revised lastly on December 7th 2021. 64 individuals are required for the trial to be held at one site." - Anonymous Online Contributor
Does this evaluation encompass elderly participants over 85 years old?
"In accordance with this clinical trial's inclusion criteria, the age range for participating patients is between 60 and 90 years of age." - Anonymous Online Contributor
Who would benefit most from participating in this trial?
"This clinical trial is enlisting 64 elderly individuals exhibiting cognitive deterioration, aged between 60 and 90. To be eligible for participation, applicants must satisfy the following criteria: comply with all home-based assessments and other procedures of the clinical trial; possess a Family Physician; have access to email services as well as internet connectivity; reside in a house or an apartment within their local community; employ either a tablet computer device or pc at home; communicate fluently in English and/or French (both written & spoken); move independently over 10 metres using any mobility aid if needed; suffer from Mild Cognitive Impairment (MCI) or Subjective" - Anonymous Online Contributor
Are individuals being enrolled in the trial at this present moment?
"Affirmative. Clinicaltrials.gov data indicates that the trial, which was first posted on July 28th 2021 and last revised December 7th 2021 is currently seeking volunteers. 64 patients are needed from a single clinical site." - Anonymous Online Contributor