Dyadic Life Review (DLR) for Cancer

University of Rochester Medical Center, Rochester, NY
Cancer+1 More ConditionsDyadic Life Review (DLR) - Behavioral
All Sexes
What conditions do you have?

Study Summary

This trial will test whether a Dyadic Life Review (DLR), adapted from Life Review Therapy, can be done effectively over telehealth with caregivers of older cancer patients, including those with Mild Cognitive Impairment (MCI).

Eligible Conditions
  • Advanced Cancer
  • Mild Cognitive Impairment

Treatment Effectiveness

Study Objectives

3 Primary · 10 Secondary · Reporting Duration: week 14

proportion of participants that consent who are approached for the study
baseline to week 14
mean change in Caregiver Reaction Scale for caregivers
mean change in Distress Thermometer and Problem list for caregivers
mean change in Dyadic Adjustment Scale-7 for caregivers
mean change in Dyadic Support Questionnaire
mean change in Geriatric Depression Scale for caregivers
mean change in PROMIS29 domains
mean change in Perceived Stress Scale for caregivers
mean change in Unidimensional Relationship Closeness Scale for caregivers
mean change in the UCLA Loneliness Score for caregivers
mean change in the correlation between caregiver and patient distress
week 14
proportion of participants that complete the study
proportion of participants who state the intervention is acceptable during a qualitative interview

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Cancer Patients
1 of 1

Experimental Treatment

80 Total Participants · 1 Treatment Group

Primary Treatment: Dyadic Life Review (DLR) · No Placebo Group · N/A

Cancer Patients
Experimental Group · 1 Intervention: Dyadic Life Review (DLR) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: week 14

Who is running the clinical trial?

University of RochesterLead Sponsor
807 Previous Clinical Trials
506,569 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,272 Previous Clinical Trials
41,230,648 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,487 Previous Clinical Trials
5,129,227 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
I'm sorry, it seems like the criterion you were about to mention got cut off. Could you please provide me with the full criterion so I can summarize it for you?
You have advanced cancer, either Stage III or Stage IV, regardless of the type of cancer.

Who else is applying?

What state do they live in?
New York25.0%
How old are they?
18 - 65100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

Frequently Asked Questions

What results are scientists hoping to glean from this clinical endeavor?

"This trial's primary outcome will be measured after two weeks and is the percentage of participants that agree to join. Secondary outcomes include changes in Dyadic Adjustment Scale-7, UCLA Loneliness Score and PROMIS29 domains scores; all of which are graded on a scale from 0 - 10 with higher numbers suggesting worse results." - Anonymous Online Contributor

Unverified Answer

Are there any available slots for participants in this research?

"Per the data hosted on clinicaltrials.gov, this medical experiment is actively enrolling patients. It was initially published on 28th March 2022 and its most recent update came through 15 June of that same year." - Anonymous Online Contributor

Unverified Answer

How many volunteers are involved in this research endeavor?

"Affirmative. According to records accessible on clinicaltrials.gov, the trial first published in March 28th 2022 is presently recruiting for 80 candidates from a single site. The listing was most recently updated on June 15th 2022." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.