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Behavioural Intervention

rTMS for Neuropsychiatric Symptoms (TAMCI Trial)

N/A
Recruiting
Led By Prasad R. Padala, MBBS MBBS
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
On stable dose of antidepressants for at least a month (if applicable)
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of 1 year
Awards & highlights

TAMCI Trial Summary

This trial will study whether or not magnetic stimulation can help treat apathy in older Veterans with memory problems.

Who is the study for?
This trial is for older Veterans with mild memory problems who show signs of apathy. They must meet specific criteria for Mild Cognitive Impairment, have a caregiver, score at least 23 on the MMSE (a test of mental function), and if taking antidepressants, be on a stable dose for one month.Check my eligibility
What is being tested?
The study tests whether Transcranial Magnetic Stimulation (TMS) can improve motivation, memory, and functioning in participants. It involves real or sham TMS over 20 sessions targeting the brain's frontal area. The study also examines genetic factors that may influence response to treatment.See study design
What are the potential side effects?
While not explicitly stated here, common side effects of TMS may include headache, scalp discomfort at the site of stimulation, tingling or spasms in facial muscles.

TAMCI Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been on the same dose of antidepressants for at least a month.

TAMCI Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Apathy Evaluation Scale Score
Secondary outcome measures
Change in Conner's Continuous Performance Test Commission Error percentage
Change in Modified Mini Mental State Examination Score
Other outcome measures
Functional Activities Questionnaire
Neuropsychiatric Inventory - Questionnaire
T-MoCA
+1 more

TAMCI Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: Apathy +, rTMS -Active Control1 Intervention
This arm will be followed without intervention
Group II: rTMSActive Control1 Intervention
This group will be randomized to receive rTMS treatment
Group III: ShamPlacebo Group1 Intervention
This group will be randomized to receive sham treatment

Find a Location

Who is running the clinical trial?

University of ArkansasOTHER
485 Previous Clinical Trials
149,748 Total Patients Enrolled
VA Office of Research and DevelopmentLead Sponsor
1,606 Previous Clinical Trials
3,305,880 Total Patients Enrolled
Central Arkansas Veterans Healthcare SystemFED
23 Previous Clinical Trials
3,415 Total Patients Enrolled

Media Library

Transcranial Magnetic Stimulation (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT03590327 — N/A
Neuropsychiatric Symptoms Research Study Groups: Apathy +, rTMS -, rTMS, Sham
Neuropsychiatric Symptoms Clinical Trial 2023: Transcranial Magnetic Stimulation Highlights & Side Effects. Trial Name: NCT03590327 — N/A
Transcranial Magnetic Stimulation (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03590327 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants still being enrolled in this experiment?

"Indeed, the clinical trial is presently recruiting participants. According to information hosted on clinicaltrials.gov, it was initially posted in November 2018 and recently updated October 2022. A total of 125 subjects are being enrolled at a single medical centre."

Answered by AI

How many participants are currently enrolled in this clinical trial?

"Affirmative. As per clinicaltrials.gov, this research is actively seeking suitable candidates; the study was first made public on November 1st 2018 and last modified on October 18th 2022. A total of 125 participants need to be recruited at a single site."

Answered by AI
~12 spots leftby Oct 2024