← Back to Search

Mindfulness Meditation (MM) Condition for Chronic Pain (LIFE Trial)

N/A
Waitlist Available
Led By Mark Jensen, Ph.D.
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age ≥18 years;
Meet criteria for having a chronic pain problem (≥3 months, with pain experienced on ≥50% of days in past 6 months);
Timeline
Screening 3 weeks
Treatment Varies
Follow Up collected via phone up to 7 weeks before tx 1, post-treatment (up to 2 mos after tx 8), and at 3- and 6-mos after tx 8]
Awards & highlights

LIFE Trial Summary

This trial will help researchers understand how three different psychological treatments - cognitive therapy, mindfulness meditation, and activation skills - can help reduce opioid use in adults with chronic pain.

Eligible Conditions
  • Chronic Pain
  • Musculoskeletal Pain

LIFE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

LIFE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~collected via phone up to 7 weeks before tx 1, post-treatment (up to 2 mos after tx 8), and at 3- and 6-mos after tx 8]
This trial's timeline: 3 weeks for screening, Varies for treatment, and collected via phone up to 7 weeks before tx 1, post-treatment (up to 2 mos after tx 8), and at 3- and 6-mos after tx 8] for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Morphine Milligram Equivalent (MME) average daily dose
Secondary outcome measures
Change in Affect
Change in Cannabis Use
Change in Medication Use
+6 more
Other outcome measures
Change in Activity Level (Actigraphy - Mechanism)
Change in Activity Level (Exercise Self-Report - Mechanism)
Change in Activity Level (Hours Spent Sitting without Exercising Self-Report)
+4 more

LIFE Trial Design

3Treatment groups
Active Control
Group I: Mindfulness Meditation (MM) ConditionActive Control1 Intervention
Participants randomized to this arm will receive training in mindfulness meditation, specifically Vipassana, which is the form of meditation typically implemented in mindfulness research. With this technique, the emphasis is placed upon developing focused attention on an object of awareness, e.g., the breath. This focus is then expanded to include a more open, non-judgmental monitoring of any sensory, emotional, or cognitive events.
Group II: Cognitive Therapy (CT) ConditionActive Control1 Intervention
Participants randomized to this arm will be taught to recognize the relationships between thoughts, feelings, behaviors, and pain.
Group III: Activation Skills (AS) ConditionActive Control1 Intervention
Participants randomized to this arm will be educated about the role of inactivity and behavioral avoidance in chronic pain and functioning. They will learn how to be aware of the activities they avoid because of pain, and how to set effective goals so that, step by step, they can start being more active and resume some activities they enjoyed in the past but are currently avoiding. Explanation and practice of a set of specific skills - including appropriate pacing skills - to facilitate an increase in appropriate activity level will be provided.

Find a Location

Who is running the clinical trial?

University of WashingtonLead Sponsor
1,732 Previous Clinical Trials
1,841,999 Total Patients Enrolled
40 Trials studying Chronic Pain
17,232 Patients Enrolled for Chronic Pain
National Center for Complementary and Integrative Health (NCCIH)NIH
829 Previous Clinical Trials
668,814 Total Patients Enrolled
45 Trials studying Chronic Pain
17,863 Patients Enrolled for Chronic Pain
The University of QueenslandOTHER
140 Previous Clinical Trials
66,101 Total Patients Enrolled
3 Trials studying Chronic Pain
1,070 Patients Enrolled for Chronic Pain

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available openings to participate in this research project?

"It appears that, according to clinicaltrials.gov records, this trial is no longer recruiting participants. Initially posted on June 16th 2020 and last updated on June 30th 2022, the study has since been closed off; however there are still 443 other trials presently open for enrollment."

Answered by AI
~24 spots leftby Mar 2025