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High-Intensity Interval Training for Breast Cancer (HEAT Trial)

N/A
Waitlist Available
Led By Diane Ehlers, PhD
Research Sponsored by University of Nebraska
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Sedentary except for casual lifestyle recreation. This is defined as self-reporting 20+ minutes of exercise physical activity on 2 or fewer days per week within the previous six months.
Fully vaccinated for COVID-19 ≥2 weeks prior to participation
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, post-intervention (week 9)
Awards & highlights

HEAT Trial Summary

This trial is testing how effective different types of exercise are for breast cancer survivors.

Eligible Conditions
  • Breast Cancer

HEAT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You don't regularly exercise or engage in physical activity, except for occasional leisure activities. This means you haven't exercised for at least 20 minutes on more than 2 days per week in the last 6 months.
Select...
You must have received a complete COVID-19 vaccination at least two weeks before participating.

HEAT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Acceptability of the exercise programs
Adherence to the exercise programs
Change in cognitive flexibility
+4 more
Secondary outcome measures
Carotid arterial wall thickness
Change in Cardiorespiratory Fitness
Endothelial function

HEAT Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: High-Intensity Interval Training (HIIT)Experimental Treatment1 Intervention
Breast cancer survivors randomized to HIIT will participate in a high-intensity interval training program for 8 weeks.
Group II: Moderate-Intensity Exercise (MOD)Active Control1 Intervention
Breast cancer survivors randomized to MOD will participate in a moderate-intensity aerobic exercise program for 8 weeks.
Group III: Usual Care (UC)Active Control1 Intervention
Individuals randomized to UC will be instructed to continue standard cancer care and engage in habitual lifestyle behaviors.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
High-Intensity Interval Training
2019
N/A
~570

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor
533 Previous Clinical Trials
1,143,864 Total Patients Enrolled
14 Trials studying Breast Cancer
1,006,295 Patients Enrolled for Breast Cancer
National Institute of General Medical Sciences (NIGMS)NIH
267 Previous Clinical Trials
248,597 Total Patients Enrolled
5 Trials studying Breast Cancer
1,177 Patients Enrolled for Breast Cancer
Diane Ehlers, PhDPrincipal InvestigatorUniversity of Nebraska
1 Previous Clinical Trials
20 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any remaining opportunities for participation in this experiment?

"According to clinicaltrials.gov, this trial is not searching for participants at present; the listing was initially posted on March 28th of 2022 and amended most recently on July 1st. Despite this, there are still 2,601 other studies actively recruiting patients."

Answered by AI

What is the purpose of this research endeavor?

"This clinical trial is primarily assessing participant adherence to the exercise program with baseline and post-intervention (Week 9) measurements. Secondary metrics for efficacy include endothelial function as estimated from brachial artery flow mediated dilation expressed in percent change, carotid arterial wall thickness measured by vascular ultrasound reported in millimeters, and peak VO2 changes assessed via a modified Balke treadmill graded exercise test protocol."

Answered by AI
~2 spots leftby Mar 2025