← Back to Search

Physical Activity for Breast Cancer (PACT Trial)

N/A
Waitlist Available
Led By Laura D Bilek, PT, PhD
Research Sponsored by University of Nebraska
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Female
Aged 21 years or older
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 month post-chemotherapy
Awards & highlights

PACT Trial Summary

This trial is testing the feasibility and acceptability of a mobile app-based behavioral intervention for women with breast cancer, as well as the preliminary efficacy of the intervention components on executive function and working memory.

Eligible Conditions
  • Breast Cancer

PACT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

PACT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month post-chemotherapy
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month post-chemotherapy for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Participant satisfaction: survey
acceptability of intervention: in-depth interview
intervention attendance
+2 more
Secondary outcome measures
Change in Auditory Verbal Learning Task (AVLT) performance
Change in N-Back task performance
Change in Spatial Working Memory task performance
+4 more
Other outcome measures
Change in cancer-related Fatigue
Momentary symptoms

PACT Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Move (tele-coaching calls, smartphone app & Move goals & badges)Experimental Treatment1 Intervention
Tele-coaching calls for Move participants will be based in social cognitive theory to encourage behavior adoption and goal setting focused on reducing prolonged sitting. Smartphone app features include activity monitoring that visualizes progress toward Move-based goals and goal achievement badges specific to Move.
Group II: Exercise (tele-coaching calls & smartphone app)Experimental Treatment1 Intervention
Tele-coaching calls for Exercise participants will be based in social cognitive theory to encourage behavior adoption and goal setting focused on engaging in 30 minutes of moderate-intensity physical activity per day (in 10+ minute bouts). Smartphone app features include activity monitoring that visualizes progress toward Exercise-based goals and goal achievement badges specific to Exercise.
Group III: Combo (Move+Exercise)Experimental Treatment1 Intervention
Includes tele-coaching that encourages behavior adoption and goal setting focused on reducing prolonged sitting and engaging in 30+ minutes of physical activity per day. Participants are able to visualize progress toward Move and Exercise goals and are eligible to receive achievement badges for Move and Exercise.
Group IV: Core Component (tele-coaching, emails, smartphone app & Fitbit)Active Control1 Intervention
All participants will receive the Core component, which includes access to weekly tele-coaching, weekly emails from the interventionist, a smartphone app, and a Fitbit monitor. Tele-coaching will include discussion of general cancer-related and wellness topics, and the smartphone app will have basic activity monitoring features.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Physical Activity
2019
Completed Phase 3
~4710

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor
533 Previous Clinical Trials
1,143,859 Total Patients Enrolled
15 Trials studying Breast Cancer
1,006,302 Patients Enrolled for Breast Cancer
National Institute of General Medical Sciences (NIGMS)NIH
267 Previous Clinical Trials
248,592 Total Patients Enrolled
6 Trials studying Breast Cancer
1,184 Patients Enrolled for Breast Cancer
Wake Forest UniversityOTHER
187 Previous Clinical Trials
153,511 Total Patients Enrolled
2 Trials studying Breast Cancer
734 Patients Enrolled for Breast Cancer

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~3 spots leftby Mar 2025