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[15O]water for Brain Metastases

Phase 1
Waitlist Available
Led By John M Hoffman, MD
Research Sponsored by University of Utah
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up estimated 2 years
Awards & highlights

Study Summary

This trial is investigating the effectiveness of FMISO in treating brain tumors.

Eligible Conditions
  • Cancer Brain Metastases

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~estimated 2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and estimated 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Determination of multi-tracer update times as related to overall survival and time to progression

Trial Design

1Treatment groups
Experimental Treatment
Group I: All ParticipantsExperimental Treatment4 Interventions
All enrolled participants will complete three imaging sessions on separate days, beginning with a research MRI, then a PET scan with FDG and [15O]water, and a PET scan with FMISO. The two PET scans will be in any order on different days within one week of each other, and preferably on consecutive days. The research MRI will be within 14 days of the first PET scan.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Magnetic Resonance Imaging
2017
Completed Phase 3
~1310
[18F]fluoro-2-deoxy-D-glucose (FDG)
2010
Completed Phase 1
~50

Find a Location

Who is running the clinical trial?

University of UtahLead Sponsor
1,088 Previous Clinical Trials
1,728,347 Total Patients Enrolled
John M Hoffman, MDPrincipal InvestigatorUniversity of Utah
7 Previous Clinical Trials
132 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~0 spots leftby Mar 2025