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Noninvasive Brain Stimulation

Transcranial Magnetic Stimulation for Enhancing Motivation in Healthy Individuals

N/A
Recruiting
Led By Jeremy Hogeveen, PhD
Research Sponsored by University of New Mexico
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 minutes post-rtms
Awards & highlights

Study Summary

This trial will test whether brain stimulation can help people make motivated decisions. 21 healthy participants will complete some tasks and questionnaires, then have an MRI scan. For the next two days, they will either have brain stimulation or a sham treatment, then repeat the tasks and MRI scan. If brain stimulation improves motivation, it could be used to treat patients with disorders that impede motivated behavior.

Who is the study for?
This trial is for healthy volunteers who have completed at least 12 years of education and can consent to participate. They must speak English fluently, have no history of seizures, no metal implants (as they'll undergo MRI scans), and not have a medical diagnosis of psychosis or mania.Check my eligibility
What is being tested?
The study tests if brain stimulation using rTMS on the dACC affects decision-making in healthy people. Participants will do tasks, get an fMRI scan, receive real or sham rTMS over two days, then repeat some tasks and scans.See study design
What are the potential side effects?
rTMS is generally safe but may cause discomfort at the stimulation site, headache, lightheadedness or tingling. There's a very low risk of seizure but this is minimized by excluding those with a seizure history.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 minutes post-rtms
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 minutes post-rtms for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in reliance on immediate expected value to guide decisions during a 3-armed Bandit reinforcement learning task.
Changes in task-related brain network activity centered around the dACC as measured by fMRI following rTMS.
Shifts in the effort-reward tradeoff.

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active rTMSActive Control1 Intervention
Participants will receive active rTMS for 10-20 minutes.
Group II: Sham rTMSPlacebo Group1 Intervention
Participants will receive sham rTMS for 10-20 minutes.

Find a Location

Who is running the clinical trial?

University of New MexicoLead Sponsor
371 Previous Clinical Trials
3,528,879 Total Patients Enrolled
Jeremy Hogeveen, PhDPrincipal InvestigatorUniversity of New Mexico

Media Library

Repetitive Transcranial Magnetic Stimulation (Noninvasive Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT04972786 — N/A
Traumatic Brain Injury Research Study Groups: Sham rTMS, Active rTMS
Traumatic Brain Injury Clinical Trial 2023: Repetitive Transcranial Magnetic Stimulation Highlights & Side Effects. Trial Name: NCT04972786 — N/A
Repetitive Transcranial Magnetic Stimulation (Noninvasive Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04972786 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who is eligible to join this research trial?

"The principal investigators are looking for 21 people between 18 and 55 years of age who have suffered from a traumatic brain injury (tbi). To be eligible, patients must possess at least 12 years of education and the ability to give informed consent without assistance."

Answered by AI

Are there currently vacancies in this clinical trial?

"Affirmative. The clinicaltrials.gov page states that this trial, first posted on August 1st 2021, is currently recruiting patients - 21 participants at one site to be exact."

Answered by AI

Is this research accommodating geriatric individuals?

"The age range for this research project is 18-55 years old, as specified in their entry criteria."

Answered by AI

What is the magnitude of participation in this medical experiment?

"Affirmative, the information available on clinicaltrials.gov signals that this scientific inquiry is currently enrolling patients. It was initially posted on August 1st 2021 and has been revised as of July 29th 2022. The trial is looking for a total of 21 individuals between one locations."

Answered by AI
~0 spots leftby Mar 2024