← Back to Search

Diagnostic Test

Neuraceq™ PET Imaging for Concussion

N/A
Waitlist Available
Led By Marc A Seltzer, MD
Research Sponsored by Dartmouth-Hitchcock Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
18-40 years of age
A minimum of 1 concussion prior to study entry
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 90 minutes after injection
Awards & highlights

Study Summary

This trial will study how well a PET scan using Neuraceq™ can detect changes in the brains of young athletes who had concussions at least 5 years ago.

Who is the study for?
This trial is for young athletes aged 18-40 who have had at least one concussion, as defined by the American Congress of Rehabilitative Medicine, and are at least one year post their first concussion. They must show signs of persistent cognitive issues. Those who can't join include pregnant individuals, people with other neurological disorders or significant illnesses, and those with current severe psychiatric diagnoses.Check my eligibility
What is being tested?
The study is testing if Neuraceq™ PET scans can reveal brain changes in athletes who've had concussions. Participants will receive an IV dose of Neuraceq™ to help detect these potential changes from injuries that occurred at least five years prior.See study design
What are the potential side effects?
While not explicitly stated here, common side effects associated with PET imaging agents like Neuraceq™ may include injection site reactions such as pain or swelling, nausea, headache, or a feeling of discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You are between 18 and 40 years old.
Select...
You have had at least one concussion before joining the study.
Select...
You must have had your first concussion at least one year ago.
Select...
You have a mild traumatic brain injury as defined by the American Congress of Rehabilitative Medicine.
Select...
People in Cohort A must show signs of ongoing problems with thinking or memory.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 90 minutes after injection
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 90 minutes after injection for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cognitive Assessment_1
Cognitive Assessment_2
Neuraceq™ PET Imaging

Trial Design

2Treatment groups
Active Control
Group I: Athletes with persistent cognitive deficits due to mild to moderate traumatic brain injury (mTBI)Active Control1 Intervention
Young athletes who have sustained one or more concussions with persistent cognitive complaints at least one year post-injury in spite of medical and cognitive treatment intervention.
Group II: Athletes with mild to moderate traumatic brain injury (mTBI) and good outcomeActive Control1 Intervention
Young athletes who have sustained one or more concussions without persistent cognitive complaints at least one year post-injury

Find a Location

Who is running the clinical trial?

Dartmouth-Hitchcock Medical CenterLead Sponsor
521 Previous Clinical Trials
2,542,384 Total Patients Enrolled
Marc A Seltzer, MDPrincipal InvestigatorDartmouth-Hitchcock Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment still available for this investigation?

"Based on information provided by clinicaltrials.gov, this study has concluded patient recruitment, with the first posting made on July 13th 2017 and the most recent update occurring on February 25th 2022. Though this trial is no longer actively recruiting patients, there are 76 other research projects currently enrolling volunteers."

Answered by AI

Is enrollment for this trial open to individuals aged fifty and above?

"The minimal entry age for this medical trial is 18, while the upper limit of eligibility lies at 40 years."

Answered by AI

Is participation in this medical study a viable option for me?

"This research study requires 15 individuals aged between 18 and 40 who have suffered a concussion, brain injury or mTBI. To be considered for the trial, prospective participants must meet the American Congress of Rehabilitative Medicine's definition of concussion-related impairments as well as having had at least one such incident within the year prior to enrollment in addition to demonstrating either subjective or objective evidence of cognitive impairment."

Answered by AI

Who else is applying?

What state do they live in?
New Hampshire
Maine
How old are they?
18 - 65
What site did they apply to?
Dartmouth-Hitchcock Medical Center
What portion of applicants met pre-screening criteria?
Met criteria
~2 spots leftby Mar 2025