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Early Rheumatoid Arthritis (RA) for Rheumatoid Arthritis (MusculRA Trial)

N/A
Waitlist Available
Led By Kim M Huffman, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Early RA defined as duration of disease/symptoms of less than 6 months (where "duration" denotes the length of time the patient has had symptoms/disease, not the length of time since RA diagnosis) AND prior to starting biologic DMARD therapy.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline
Awards & highlights

MusculRA Trial Summary

This trial will study whether early rheumatoid arthritis (RA) patients have different skeletal muscle biomechanical properties than healthy controls, and whether those properties are related to disability and mortality in RA patients.

Eligible Conditions
  • Rheumatoid Arthritis
  • Healthy Controls

MusculRA Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have been experiencing symptoms of rheumatoid arthritis for less than 6 months and have not yet started treatment with biologic drugs.

MusculRA Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Muscle stiffness and elasticity
Secondary outcome measures
Janus kinase/signal transducers and activators of transcription 3 pathway (JAK/STAT3) signaling in skeletal muscle
Myobundle function

MusculRA Trial Design

2Treatment groups
Experimental Treatment
Group I: Early Rheumatoid Arthritis (RA)Experimental Treatment9 Interventions
Early RA defined as duration of disease/symptoms of less than 6 months (where "duration" denotes the length of time the patient has had symptoms/disease, not the length of time since RA diagnosis) AND prior to starting biologic Disease-modifying anti-rheumatic drugs (bDMARD) therapy
Group II: Age-, Sex-, BMI-matched Healthy ControlsExperimental Treatment9 Interventions
Healthy Controls.

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,351 Previous Clinical Trials
3,409,525 Total Patients Enrolled
11 Trials studying Rheumatoid Arthritis
2,133 Patients Enrolled for Rheumatoid Arthritis
Gilead SciencesIndustry Sponsor
1,077 Previous Clinical Trials
836,929 Total Patients Enrolled
15 Trials studying Rheumatoid Arthritis
7,692 Patients Enrolled for Rheumatoid Arthritis
Kim M Huffman, MDPrincipal InvestigatorDuke University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there currently any opportunities to participate in this clinical trial?

"Affirmative. Clinicaltrials.gov shows that, since its inception on September 9th 2020, this trial is still recruiting participants for a total of 30 patients from one medical site. The data was last updated on June 6th 2022."

Answered by AI

Are participants of this trial required to be over twenty years old?

"The enrolment criteria for this trial stipulates that individuals must be between 25 and 75 years old. Those younger than 18 have 51 studies available to them, while those older than 65 can explore 337 different options."

Answered by AI

How many participants have been recruited to participate in this research endeavor?

"Affirmative. Clinicaltrials.gov reveals that this clinical experiment is presently enrolling participants, having first been posted on September 9th 2020 and most recently updated on June 6th 2022. 30 individuals are required from one medical site to complete the trial."

Answered by AI

Are there any requirements for participation in this scientific experiment?

"Qualifying patients should be aged between 25 and 75, with a confirmed diagnosis of rheumatoid arthritis. This medical experiment will accept 30 individuals in total."

Answered by AI

Who else is applying?

What state do they live in?
North Carolina
How old are they?
65+
What site did they apply to?
Duke Center for Living
What portion of applicants met pre-screening criteria?
Met criteria

How responsive is this trial?

Typically responds via
Email
Most responsive sites:
  1. Duke Center for Living: < 48 hours
Average response time
  • < 2 Days
~5 spots leftby Mar 2025