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Mindfulness-Based Stress Reduction (MBSR) for Depression

N/A
Waitlist Available
Led By Marc Brackett, PhD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Currently enrolled as a full-time Yale College undergraduate student
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and week 22
Awards & highlights

Study Summary

This trial will test the efficacy of two 8-week online interventions, CCT and MBSR, to promote social well-being and mental health in diverse university students, compared to a WL control group.

Eligible Conditions
  • Depression
  • Anxiety
  • Stress
  • Burnout
  • Emotion Regulation
  • Social Acceptance
  • Loneliness
  • Compassion

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and week 22
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and week 22 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from Baseline in Loneliness on the 4-point UCLA-Loneliness Scale Short-Form (LS-SF) at Week 10 (Post-Test)
Change from Baseline in Perceived Social Support on the 5-point Medical Outcomes Study-Social Support Survey (MOS-SSS) at Week 10 (Post-Test)
Change from Baseline in Social Connectedness on the 6-point Social Connectedness Scale-Revised (SCS-R) at Week 10 (Post-Test)
Secondary outcome measures
Anxiety
Mental Depression
Change from Baseline in Happiness on the 7-point Subjective Happiness Scale (SHS) at Week 10 (Post-Test)
+3 more
Other outcome measures
Change from Baseline in Daily Negative Mental Health on the Latent Factor-Scored Daily Negative Mental Health Index (D-NMHI) at Week 10 (Post-Test)
Change from Baseline in Daily Positive Mental Health on the Latent Factor-Scored Daily Positive Mental Health Index (D-PMHI) at Week 10 (Post-Test)
Change from Baseline in Daily Social Well-Being on the Latent Factor-Scored Daily Social Well-Being Index (D-SWI) at Week 10 (Post-Test)
+12 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Mindfulness-Based InterventionExperimental Treatment1 Intervention
Participants in this condition are assigned to an empirically supported 8-week online mindfulness-based intervention protocol. The intervention includes a weekly 2-hour educational session, a recommendation of 15-30 minutes of daily meditation, and an optional 6-hour one-day retreat.
Group II: Compassion-Based InterventionExperimental Treatment1 Intervention
Participants in this condition are assigned to an empirically supported 8-week online compassion-based intervention protocol. The intervention includes a weekly 2-hour educational session and a recommendation of 15-30-mins of daily meditation, and real-world assignments to practice compassion.
Group III: Waitlist Control (WL)Active Control1 Intervention
The WL control group will complete all study assessments on the same schedule as the intervention arms. At the time of the final follow-up assessment, participants will be randomly assigned to one of the interventions (CCT or MBSR) with the same instructors.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Compassion Cultivation Training (CCT)
2022
N/A
~290
Mindfulness-Based Stress Reduction (MBSR)
2018
Completed Phase 2
~1430

Find a Location

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,837 Previous Clinical Trials
2,728,123 Total Patients Enrolled
63 Trials studying Depression
20,356 Patients Enrolled for Depression
Marc Brackett, PhDPrincipal InvestigatorYale University
James Floman, PhDPrincipal InvestigatorYale University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Connecticut
How old are they?
18 - 65
What site did they apply to?
Yale Center for Emotional Intelligence
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
~94 spots leftby Mar 2025